Physiology of blood

Question 1

I. Parameters for Blood physiology
1. Red blood cell count (RBC, Erythrocytes)

Answer 1

Male: 4.5-5.5 million /µL blood
Female: 3.9-5.3 million /µL blood

Question 2

I. Parameters for Blood physiology
2. Thrombocyte count (Platelets)

Answer 2

2.5-3 x 10^5 / µL blood

Question 3

I. Parameters for Blood physiology
3. White blood cell count (WBC, Leukocytes)

Answer 3

3-12 x 10^3 / µL blood

Question 4

I. Parameters for Blood physiology
4A. Percentage of different white blood cell types
=> Neutrophil granulocyte?

Answer 4

60-70%

Question 5

I. Parameters for Blood physiology
4B. Percentage of different white blood cell types
=> Neutrophil Lymphocyte?

Answer 5

25-30%

Question 6

I. Parameters for Blood physiology
4C. Percentage of different white blood cell types
=> Monocyte?

Answer 6

4-8%

Question 7

I. Parameters for Blood physiology
4D. Percentage of different white blood cell types
=> Eosinophil granulocyte?

Answer 7

2-4%

Question 8

I. Parameters for Blood physiology
4E. Percentage of different white blood cell types
=> Basophil granulocyte?

Answer 8

0-1%

Question 9

I. Parameters for Blood physiology
5. What is the general composition of the blood plasma?

Answer 9

90% water
8% plasma proteins
2% other organic compounds

Question 10

I. Parameters for Blood physiology
6. What is the Normal value of blood?

Answer 10

60 – 80 mL/kg
70kg adult has 5L of blood

Question 11

I. Parameters for Blood physiology
7. What is the normal Amount of hemoglobin?

Answer 11

2.2 - 2.5 mM (tetramer)

Question 12

I. Parameters for Blood physiology
8. What is the normal value of Mean corpuscular volume (MCV)?

Answer 12

90 fL

Question 13

I. Parameters for Blood physiology
9. What is the normal value of Mean corpuscular hemoglobin (MCH)?

Answer 13

0.5 fmol/ cell
(Note: fmol mean femtomole (1fmol = 10-15 moles))

Question 14

II. Figures of Blood Physiology
37. Oxyhemoglobin dissociation curve in blood. Give normal values related to arterial and venous blood on both axes!

Answer 14

Question 15

II. Figures of Blood Physiology
38. Oxyhemoglobin dissociation curve in blood with altered pH (decreased and increased from normal). Give normal values related to arterial and venous blood on both axes!

Answer 15

Question 16

II. Figures of Blood Physiology
40. Mechanism of CO2 uptake by red blood cells in tissues.

Answer 16

Question 17

II. Figures of Blood Physiology
41. Mechanism of CO2 release by red blood cells in lung capillaries.

Answer 17

Question 18

II. Figures of Blood Physiology
42. Draw a figure representing the role of Cl–HCO3- exchanger in the mechanism of hemolysis of RBCs in isoosmotic NH4Cl solution!

Answer 18

Question 19

II. Figures of Blood Physiology
39. Oxyhemoglobin dissociation curve in blood of a mother and her fetus. Give normal values related to arterial and venous blood of the mother on both axes!

Answer 19