8.6A. Physiology of equilibrium. Flashcards
I. Vestibular system
1. What is the role of Vestibular system?
The vestibular system is responsible for the sense of equilibrium – a form of proprioception.
I. Vestibular system
2. What is the role of vestibular apparatus?
The vestibular apparatus detects the position, linear acceleration, and rotation of the head.
- To accomplish this, it uses two different apparatuses involving hair cells.
-> It includes the anterior, posterior and horizontal Semicircular canals, as well as the Utricle and Saccule (otolithic organs)
I. Vestibular system
3. Will the endolymph fill vestibular system? What are the consequences?
The endolymph will fill the vestibular system, but it is far away from the place of the production
-> the [K+] remains the same, but the electric potential will disappear (0mV), because the distance is too large and it will be attenuated
II. Vestibule (vestibular apparatus)
1. Describe the structure of Vestibule (vestibular apparatus)?
- The vestibular portion of the membranous labyrinth in the inner ear
- The vestibular portion has 5 sensory structures: 2 otolithic organs and 3 semicircular
canals
II. Vestibule (vestibular apparatus)
2A. List the Otholotic organs
saccule and utricle (macula + otolithic membrane)
II. Vestibule (vestibular apparatus)
2B. What are the characteristics of Otholotic organs?
- Located near the center of the labyrinth
- Filled with endolymph, but surrounded by perilymph
- Between the endo and perilymph, we have the endothelial layer, where we can find
hair cells
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2C. What is the role of Vestibular dark cells?
secrete K+ into the endolymph
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2D1. What are the features of macula?
Macula: contains hair cells
- The stereovilli of the hair cells project into the gelatinous otolithic membrane
- Otolithic membrane = mass of mucopolysaccharides + otoliths (crystals/salts =
CaCO3)
- Otoliths make the otolithic membrane denser than the surrounding endolymph
- If we change the position of this system or have a gravity force, the otoliths will cause the otolithic membrane to move -> mechanical stimulus (deflecting stereovilli etc.)
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2D2. Where do The stereovilli of the hair cells project into?
The stereovilli of the hair cells project into the gelatinous otolithic membrane
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2D3. What is the structure of Otolithic membrane
mass of mucopolysaccharides + otoliths (crystals/salts =
CaCO3)
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2E. What is the orientation of macula?
- Saccule = vertical (hair cells towards striola)
- Utricle = horizontal (hair cells away from striola)
=> Get a 3-dimensional-system and this is why the entire otolithic organ will respond (whatever direction) to change of mechanical stimulus
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2F. What are the features of striola?
- The hair cells of the macula are oriented in relation to a groove called the striola (reversal line), which runs through the middle of each macula.
- The striola is useful, because APs from hair cells will increase on one side of the striola and decrease on the other side, which creates a strong contrast that makes interpretation easier
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2G. Explain activation of macula
(1) Change of position of head and (2) linear acceleration of head, will serve as a mechanical stimulus: cause movement of otolithic membrane
-> deflection of stereovilli
-> activation
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2H. What is the innervation of Otholotic organs?
Vestibular N (CNVIII)
II. Vestibule (vestibular apparatus) - Otholotic organs = saccule and utricle (macula + otolithic membrane)
2I. Describe afferentation of Otholotic organs
- Innervate type 1 and type 2 hair cells
- Body of the cell forms ganglion: Scarpa’s ganglion
- Ipsilateral ending of nerve cells in the vestibular nuclei