physiology - body fluids Flashcards
Primary transport system between cells
nutrition
waste
signals
Fluid Compartments:
a) total body water
b) ICF
c) ECF
d) plasma
e) Interstitial fluid
a) 42 L ( 60% OF MASS)
b) 28L
c) 14L
d) 3L
e) 11 L
the boundary between Intracellular Fluid/Interstitial Fluid
it is the cell membrane
semi permable
membrane embedded w proteins which act as ion channels and ion pumps
boundaries between Interstitial Fluid/Plasma
boundary is capillary wall
Permeable to small molecules
Composition of intracellular fluid ICF
Na+ low
Cl- high
K+ high
Composition of Interstitial Fluid (IF)
opposite of ICF
tonicity
the effect on solute concentration on cell volume
what is hypotonic solution
what happens when you put cell in this solution
- solution that has a lower conc of solute compared to the cytosol.
- solute cannot pass thru only h20. , the cell swells
what is hypertonic solution
what happens if you put a cell in this solution
solution that has greater conc. of solute compared to cytosol
the cell loses water to balance out the conc on either side of cell and therefore cell shrinks
Lymphatic system … what does it do
fluid leaks out of cardiovascular system
Lymphatic system collects the lymph and brings it back to the cardiovascular system
Systemic capillaries
allow the exchange of materials between tissues and blood eg nutrients , waste , gas AND WATER
lymphatic drainage
3l a day in not reabsorbed in capillaries or venules
it enter lymph vessels and pumped to lymph nodes
and then re enters circulation near right atrium
starlings law of capillaries pt1
whats happening when fluid crosses the capillaries
when the blood enters capillary from arteriole it has a bp of 37mmMg moving out of the capillary … this pressure on the wall allows fluids to leave the capillary
when the blood in the capillary in the other end has a 17mmMg
starlings law of capillaries pt2
the colloid OP caused by plasma proteins causes water to be reabsorbed the capillary … this pressure stays the same throughout
OUTWARD PRESSURE > INWARD PRESSURE:
the main things is that fluid leaves capillary and enters interstitial fluid
how is liver failure caused
when there is a fall in plasma proteins ….
this leads to colloid OP fall
reduced inwards flow
accumulation of fluid in the tissues aka oedema