IIP : Multimodality imaging for TVD and Image Registration

Question 1

3 basic types of MRI weighing used in clinical practice:

Answer 1

• Proton density (PD) weighted
• T1weighted
• T2 weighted

Question 2

MRI: T1

Answer 2

fluid containing structures are dark
good for anatomical detail , vascular changes
poor for imaging normal vs abnormal tissues

Question 3

T2

Answer 3

fluid is bright

less anatomical detail
very good contrast between normal and abnormal tissue

Question 4

Functional MRI (fMRI) is used to understand how….

Answer 4

different parts of the brain responds to external stimulation

• blood oxygenation increases during brain activity
• specific areas of cortex are activated during different tasks

Question 5

MRI:TVD
Advantages:

Answer 5

non-ionising

high contrast resolution offers better soft tissue localisation

Question 6

MRI:TVD
disadvantages:

Answer 6

1. cant be used in dose calculations as pixel intensities are not related to electron intensities
2. metallic implants cause problems
3. running and maintenance costs are high
4. Inherent image distortion at edge of image
5. not as available as CT

Question 7

PET/CT: TVD

Radionuclide imaging

Answer 7

uses (18F-FDG)

as cancer cells has a higher glucose metabolism than normal cells

Question 8

PET/CT: TVD

Diagnosis

Answer 8

help stage tumours more accurately

can detect disease at a earlier stage

Question 9

PET/CT: TVD

functional imaging

Answer 9

evaluates biochem and physiology

evaluates adequate coverage of tumour volume including nodes

Question 10

PET/CT:TVD

Advantages:

Answer 10

functional and structural anatomy
assessing extent of disease
Differentiates between tumour and scar tissue

Question 11

PET/CT:TVD

Disadvantages:

Answer 11

expensive
large ionising dose
image registration can be difficult
Specificity is decreased with inflammation
workflow can delay planning process if issues with patient prep