Pharmacology - Week 2

Question 1

What does the dose-response curve represents

Answer 1

Measure the intensity of response in relation to a drug given

Question 2

What’s potency

Answer 2

Related to the amount of drug needed to produce an effect

Question 3

What’s efficacy

Answer 3

Maximal effect of a drug regardless of dose

Question 4

What’s the therapeutic index

Answer 4

TI=LD50/ED50

Question 5

The greater the TI, the safer the drug. T/F?

Answer 5

True

Question 6

Give an example of a lower TI drug

Answer 6

Digoxin - 💔

Question 7

What’s the first pass effect

Question 8

What’s an agonist and antagonist drug

Answer 8

Agonist has affinity for a receptor
Antagonist counteracts the action of the agonist

Question 9

Types of antagonist. Explain each

Answer 9

Competitive - binds to a receptor that has affinity for but no effect
Noncompetitive - binds to a receptor different from the agonist but reduces its max response
Physiologic - same as above but also produces an opposite effect

Question 10

Explain passive transfer