Pharmacology Quiz 1 (Chapter 1-3) Flashcards

1
Q

Drug definition

A

any chemical that affects living processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pharmacology

A

study of drugs and interactions with living things

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Clinical Pharmacology

A

study of drugs in humans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Therapeutics

A

use of drugs to diagnose, prevent, or treat diseases or pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

In a perfect world, What are the ideal functions of an ideal drug? (3)

A

*Effective
*Safe
*Selective

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In a perfect world, what are the additional functions an ideal drug would have?

A

Reversible (null/metabolize)
Predictability
Ease of administering (convenient route/ low dose regimen, pt adherence, less risk)
Freedom drug interaction (no drug to drug interactions)
Low cost
Chemical stability with the same potency
Simple generic name

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the ultimate goal of a therapeutic drug?

A

provide maximum benefits with minimum harm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A drug becomes toxic when given

A

too much of a dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

A drug becomes ineffective if given

A

too little of a dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F
No 2 people respond the same to a drug.

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the sources of individual variation?

A

Pharmacokinetics
Pharmacodynamics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the ultimate concern of administering a drug?

A

Intensity of response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Administration variations

A

poor patient adherence
Medication errors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pharmacokinetics variations

A

absorption
distribution
metabolism
excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pharmacokinetics definition

A

how drug moves through the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pharmacodynamics

A

how the drug affects the body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What determines the nature and intensity of the response?

A

pharmacodynamics

18
Q

Nursing Process: Systematic approach

A

methodical
logical
orderly

19
Q

What guides the nursing process decisions?

A

medication (stop med errors)
safety (pt care and education)
regulation
checks and balances

20
Q

The prescribed dose:
Method and Errors

A

Administration

-Med errors (7 rights)
-Pt adherence

21
Q

Concentration at the site:
Pharmacokinetics variation and errors

A

Pharmacokinetics
- absorption
- distribution
- metabolism
- excretion

22
Q

AAPIE

A

(Pre) Assessment and Analysis
Planning
Implementation
Evaluation

23
Q

Concentration at the site:
Pharmacodynamics variation and errors

A
  • drug receptor
  • pt functional state
  • placebo effects
24
Q

Concentration at the site:
Sources of variation and errors

A
  • physiological
  • pathological
25
Q

(Pre) Assessment includes

A

-Baseline = history, physical exam, lab results, BP/VS, blood sugar, height, and weight
-High Risk = liver/kidney, impairment, genetic, allergies, pregnancy, elderly, pediatric
-Capacity for Self-care

26
Q

Analysis includes

A

Nurse Diagnosis
- Judge: appropriate prescription drug regimen
- Identity: potential health problem that drug can cause

27
Q

Planning includes

A

Establish objective criteria for evaluation
- define goals
- set priority
- ID specific intervention

28
Q

Implementation includes

A

drug administration to education to intervention
- know when early signs, med response, manage toxicity
- therapeutic effects, minimize adverse effects and drug effects, make prn decision

29
Q

Evaluation includes

A

therapeutic response
adverse drug reaction and interaction

30
Q

What type of drug trials do drugs go through?

A

randomized control trial (volunteer or pt well-established)
randomization
blinding (single or double)

31
Q

What trial is the best for accurate results?

A

double-blind (no one knows what med is given)

32
Q

Stages of Drug Development

A

1- preclinical testing
2- clinical testing stage 1: healthy people tested on metabolism, pharmacokinetics, and biological effects
3- stage 2: therapeutic use and dose range
4- stage 3: safety and effectiveness
5- Post clinical: surveillance

33
Q

After what stage does FDA give approval?

A

Stage 3
before post clinicals

34
Q

Tylenol generic name

A

acetaminophen

35
Q

Lithobid generic name

A

Lithium Carbonate

36
Q

Toprol, Lopressor generic name

A

Metoprolol succinate

37
Q

Label Requirements by Pure Food and Drug Act 1906

A
  • plain, readable, user friendly
  • active ingredient and inactive ingredients
  • uses
  • warnings
  • directions
    Educate pt on drug labels and approvals
38
Q

OTC drugs are used for illness ___ % of the time.

A

60

39
Q

Approximately how much money do OTC companies make each year?

A

30 billion

40
Q

What percentage of drugs is initially self treated with OTC drugs?

A

60-90

41
Q

What is the average number of OTC drugs in a household?

A

24

42
Q

Clinical testing is not done on these individuals

A

women and children