Pharmacology 1 - Uterorelaxant & Uterostimulant Flashcards

1
Q

Fungsi obat tokolitik

A

B2 selektif, merelaksasikan dan mendelay kontraksi muncul selama beberapa hari

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2
Q

Contoh obat tokolitik

A

Fenoterol, Ritodrine

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3
Q

Efek samping tokolitik

A

Takikardi, Vasodilatasi akibat stimulasi receptor Beta 1

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4
Q

Jika pasien dengan kontraksi preterm beserta penyakit jantung maka obat yang diberikan

A

Magnesium sulfate IV/IM

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5
Q

Contoh obat uterostimulant

A

Oxytocin, Prostaglandin

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6
Q

Mekanisme aksi uterostimulant

A
  1. Kontraksi otot uterus dari PGF2, TXA2, dan PGE2
  2. PGI2 dan PGE2 menyebabkan relaksasi
  3. PGF2 dan oxytocin perlu untuk onset parturisi
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7
Q

Efek samping dari misoprostol

A

Shivering

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8
Q

Prostaglandin biasanya digunakan bersamaan dengan

A

Misoprostol, sulprostone, dinoprostone

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9
Q

Efek samping prostaglandin

A
  1. Mual, muntah, diare
  2. Bronkokonstriktor, TD turun
  3. Gangguan pencernaan
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