Parasit - Toxoplasma gondii & Trichomonas vaginalis Flashcards

1
Q

Habitat Trichomonas vaginalis

A

Wanita : vagina

Laki-laki : uretra, epididimis, testis

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2
Q

Morfologi Trichomonas vaginalis

A
  1. Bentuk oval seperti jambu
  2. 4 flagel anterior, 1 flagel pada membrana undulans
  3. Aksostil
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3
Q

Cara infeksi Trichomonas vaginalis

A

Hubungan seksual, kontak langsung

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4
Q

Patologi infeksi trichomonas vaginalis

A
  1. Dinding vagina : hiperemis, lunak, peteki, bergranula
  2. Mukosa : strawberry vagina
  3. Permukaan vagina : sekret berbusa, kekuningan
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5
Q

Gejala infeksi trichomonas vaginalis

A

Pria : uretritis, prostatovesiculitis

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6
Q

Tatalaksana trichomoniasis

A

Kebersihan vagina, pemeriksaan suami-istri (sumber infeksi), diberi obat oral dan lokal Metronodazole

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7
Q

Ciri Toxoplasma gondii

A
  1. Intraseluler, namun dapat motil pada ekstraseluler
  2. Membentuk endozoit (tropozoit intraseluler)
  3. Takizoit (proliferatif)
  4. Bradizoit (proliferasi lambat, infeksi kronis)
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8
Q

Stadium toxoplasma gondii

A

Pseudokista (akut), Kista (kronis)

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9
Q

Siklus hidup toxoplasma gondii

A

Skizon dan gametosit (usus kucing) - oocyst (feses) - sporocyst - sporozoit

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10
Q

Ciri takizoit

A
  1. Cepat berproliferasi
  2. Bentuk bulan sabit
  3. Tempat : Paru, jantung, organ limfoid, SSP
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11
Q

Gejala toxoplasmosis

A

Asymptomatik, gejala infeksi umum (menggigil, demam, myalgia dll), Berat (hepatitis, encephalomyelitis, myocarditis, retino choroiditis)

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12
Q

Gejala toxoplasmosis kongenital

A
  1. Meningoensefalitis, myocarditis, pneumonia atipik
  2. Retinochoroiditis
  3. Sabin Tetrad
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13
Q

Sabin Tetrad

A

Retinochoroiditis, Kalsifikasi serebral, Hidrosefalus/mikrosefalus, Gangguan psikomotor

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14
Q

Diagnosis toxoplasmosis

A
  1. Sabin-Feldman dye test
  2. Toxoplasmin skin test
  3. IFAT
  4. Elisa
  5. Kultur buffy coat
  6. Inokulasi hewan
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15
Q

Jika ditemukan titer IgM positif dan IgG negatif/rendah pada toxoplasmosis maka

A

Infeksi awal

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16
Q

Jika IgM positif pada toxoplasmosis kongenital artinya

A

Terbentuk antibodi secara aktif

17
Q

Pengobatan toxoplasmosis

A

Pyrimethamine 25-50 mg/hari selama 1 bulan
Trisulfapyrimidines 2-6 gram/hari selama 1 bulan

Berikan asam folat (karena menghambat aktivitas sumsum tulang)