Pharmacokinetics And Dynamics

Question 1

What is your understanding on pharmacokinetics and dynamics

Answer 1

Pharmacokinetics deals with the movement of drugs in the body from time it enters the body to leaving the body

Pharmacodynamics is the study of the changes that drugs causes to our body when administered

Question 2

Drugs can be absorbed through

Answer 2

Passive diffusion
Facilitated diffusion
Active transport
Endocytosis

Question 3

Most drugs are absorbed by

Answer 3

Passive diffusion

Question 4

Diffusion is directly proportional to

Answer 4

Conc * temperature *surface area
____________________________________
Thickness of membrane * size of molecule

Question 5

When a drug passes first through the liver to be metabolismed it is called

Answer 5

First pass metabolism

Question 6

Acidic drug bonds to what plasma protein

Answer 6

Albumin

Question 7

Basic drugs binds to what plasma protein

Answer 7

Alpha 1 acid glycoprotein

Question 8

Bioavailability

Answer 8

Is the amount of drugs that reaches the BLOOD in an unchanged form( without metabolized) from its administered route

Eg I.v bioavailability is 100% while oral is 50% because IV is directly into the blood while oral will reach the liver first and half of it is metabolized for the xcretion