Antidepressants Flashcards
What is depression
Depression is a disorder of the mood
What are the types of depression
Neurotic
And pshycic
Unipolar depression affects how many percent of the population
75%
Bipolar depression affects how many percent of the population
25%
The pharmacology of depression is
Depression is caused by the decrease in biogenic monoamines in the body nd cns
Ie serotonin and neoepinephrine
Antidepressant drugs that act by inhibiting the reuptake of serotonin
SSRI selective serotonin reuptake inhibitors
TCA tricyclic antidepressant
NDRI
SNRI
MAOi mechanism of action is by
Inhibits monoamine oxidase enzyme with breaks down monoamines
TCA mechanism of action
Non selective reuptake inhibition of monoamines
What is the pharmacology explaination of depression
Depression is reduced serotonin level in the brain
Nefazodone and trazodone are what type of antidepressant
Atypical antidepressant
Dey don’t work in the normal way antidepressants normally work
The antidepressant drug class that prevents the reuptake of monoamine includes
TCA
SSRI
NDRI
Tca antidepressant drugs mechanism of action
They prevent the reuptake of any mono amine
Acetyl choline histamine serotonin
Tca antidepressant drugs effect include
Serotonin syndrome…if combined with SSRI
Dry mouth
Adrenergic overstimulation
Antidepressant drugs that increase the production of serotonin
Trazadone
Nefazodone
TCA DRUGS INCLUDE
ANTIDEPC
amytrptaline
Neotryptaline
Trimipramine
Imipramine
Protryptaline
Clomiprimine
