Tetracyclines And Chlormaphenicol Flashcards

1
Q

Tetracyclines are broad or narrow spectrum

A

Broad spectrum

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2
Q

Mechanism of action of tetracycline

A

Prevents the binding of aminoacyl tRNA to the ribosome

Which reads the mRNA codon

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3
Q

Tetracycline is Bacteriocidial or bacteriostatic

A

Bacteriostatic

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4
Q

Mode of administration of tetracycline

A

Orally
Preferably on an empty stomach

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5
Q

Chloramphenicol mode of action is by

A

Inhibiting peptide bond formation used for enlongation of amino acids at the 50s ribosome

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6
Q

Chloramphenicol is Bacteriocidial or static

A

Bacterostatic

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7
Q

Chloramphenicol a narrow or broad spectrum antibiotics

A

Broad spectrum

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8
Q

Tetracycline which are lipophillic in nature is

A

Doxycycline and minocycline

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9
Q

What tetracycline are easily absorbed in the git

A

Doxycycline and minocycline

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10
Q

All tetracycline are excreted in the urine except

And there excretion point

A

Minocycline and doxycycline

Feaces

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11
Q

Chloramphenicol is synthesized from

A

Streptomyces Venezuelae

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12
Q

Chloramphenicol is mainly used during

A

Life threatening meningitis or ricketsettal infection

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13
Q

Chloramphenicol moves through cell membranes by what mechanism

A

Facilitated diffusion

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