Epilepsy /anticonvulsant

Question 1

Epilepsy is a condition that results from

Answer 1

Too much excitatory amines at the cns

Question 2

Mechanism of anticonvulsant include

Answer 2

Increase of gaba at
Increase outward movement of K+ efflux
Decrease in glutamate
Inhibiting na+ and ca+ channel

Question 3

Major excitatory protein of the cns is

Answer 3

Glutamate

Question 4

GABA a receptor does

Answer 4

Influx of chlorine

Question 5

Barbiturate mechanism of action is

Answer 5

Acting upon GABA a receptor inducing an influx of chlorine cl-

Question 6

Barbiturates and benzodiazepines mechanism of action is

Answer 6

Attaching to GABA A and causing an influx of chlorine into the cell

Question 7

What are barbiturates

Answer 7

They are cns depressants that cause drowsiness

Question 8

Longest acting barbiturates is

Answer 8

Phenobarbital

Question 9

Immediate/ partial long acting barbiturates is

Answer 9

Pentobarbital

Question 10

Short acting barbiturates is

Answer 10

Secobarbital

Question 11

Benzodiazepines are what type of cns drug

Answer 11

Anxiolytics (anti anxiety drugs

Question 12

Effect of barbiturates to REM

Answer 12

Barbiturates increases REM 2 phase and
Decreases REM 3,4&5

Question 13

Benzodiazepines drugs end in
( LAM & PAM)

Answer 13

Eg dizepam, Midazolam, lorazepam

Question 14

Short acting benzodiazepines is

Answer 14

Midazolam
Triazolam

Question 15

Long acting benzodiazepines is

Answer 15

Diazepam
Flurazepam

Question 16

Intermediate acting benzodiazepines is

Answer 16

Lorazepam
Alfrazolam
Temazepam

Question 17

Flumazenil is an antitode for overdose of benzodiazepines

Question 18

What drug is sued to treat overdose ofbenzodiazepines

Answer 18

flumazenil