Leprosy

Question 1

Leprosy is an infection caused by

Answer 1

Mycobacterium leprea

Question 2

Leprosy is also known as what disease

Answer 2

Hansen disease

Question 3

Leprosy with solitary skin lesions that are asymmetrical in the skin is what type

Answer 3

Tuberculoid leprosy

Question 4

Leprosy with skin macules is

Answer 4

Lepratomous leprosy

Question 5

Leprosy that is non infectious with no bacterium sample present and few skin lesions are what type according to WHO is

Answer 5

Paucibacilliary leprosy

Question 6

Leprosy that is infectious many bacterium sample present and more skin lesions are what type

Answer 6

Multibacilliary leprosy

Question 7

Mycobacterium leprae causes what

Answer 7

Leprosy

Question 8

We detect mycobacterium leprea by

Answer 8

Doing a biopsy and lepromin test

Question 9

Drugs used in treating leprosy includes

Answer 9

Rimfampin
Dapsone
Clifazimine

Question 10

The Bacteriocidial drugs used in treating leprosy by inhibiting rna transcription is

Answer 10

Rimfampin

Question 11

Dapsone mechanism of action is

Answer 11

Ihibiting dihydropteroate synthase in folate synthesis

Question 12

Leprosy drugs are administered through

Answer 12

Orally

Question 13

In lepromin test how is it carried

Answer 13

The test requires injecting an already inactivated leprae mycobacterium specifically in the UPPER LIMBS

Question 14

Which of these drugs is a Bacteriocidial drug (state the uses of each drugs)

Dapsone
Erythromycin
Rimfampin in
Clofazimine

Answer 14

Rifampicin

Question 15

The leprosy drugs that renders leprosy patient non contagious is

Answer 15

Rifampicin

Question 16

Rifampicin works by

Answer 16

Inhibiting rna transcription by stopping the interaction of the beta subunit to rna polymerase

Question 17

The leprosy drugs that accumulate in the kidney liver skin and muscle is

Answer 17

Dapsone

Question 18

How is dapsone eliminated

Answer 18

It undergoes liver acetylation and then exerted

Question 19

Dapsone adverse effect is

Answer 19

Hemolysis in G6PD deficiency
And neuropathic disorder

Question 20

The leprosy drug that is a liver enzyme inducer is

Answer 20

Rifampicin

Question 21

Rifampicin kills leprosy in how many days

Answer 21

3-7 days

Question 22

Mode of administration of leprosy drug is

Answer 22

Orally

Question 23

Multidrug treatment of leprosy is by using

Answer 23

3 of the leprosy drugs to manage m leprea especially those ones with dapsone resistance

Question 24

Leprea reaction is gotten from

Answer 24

Lepratomous leprosy infection

Question 25

Sulfone syndrome is a leprosy reaction gotten from

Answer 25

Dapsone treatment