Beta Lactam

Question 1

1st generation cephalosporins are effective against

Answer 1

Gram positive bacteria in respiratory and urinary tract

Question 2

2nd generation cephalosporins are effective against

Answer 2

Gram negative + anaerobes

Question 3

3rd generation cephalosporins are effective against

Answer 3

Gram negative

Question 4

4th generation cephalosporins are effective against

Answer 4

Both gram negative and positive

Question 5

Beta lactam drugs destroy cell wall synthesis by

Answer 5

Inhibiting transpeptidase

Question 6

Transpeptidase does what to peptidoglycan ring

Answer 6

Cross links peptide chain and fly an chain

Question 7

Example of beta lactam drugs

Answer 7

Monobactams
Penicillin
Carbapenem
Cephalosporin

Question 8

Naturally occurring penicillin include

Answer 8

Penicillin G and V

Question 9

Penicillin G is effective against gram ———- bacteria

Answer 9

Positive

Question 10

Penicillin G is given

Answer 10

Parenterally

Question 11

WhT naturally occurring penicillin is broad spectrum

Answer 11

Penicillin V

Question 12

WhT naturally occurring penicillin is narrow spectrum

Answer 12

Penicillin G

Question 13

WhT naturally occurring penicillin is given in the mouth

Answer 13

Penicillin V

Question 14

WhT naturally occurring penicillin is effective against gram negative bacteria

Answer 14

Penicillin V

Question 15

Cephalosporin has a ————— spectrum than penicillin

Answer 15

Broader

Question 16

Transpeptidase is also called the

Answer 16

Penicillin binding protein (pbp)