Antipsychotics Flashcards

1
Q

Schizophrenia pathology is

A

High dopamine in the Mesolimbic and mesocortical tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mechanism of action of antipsychotic drugs

A

They inhibit D2receptor in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Chlorpromazine is what type of drugs

A

Antipsychotic drug

A dopamine receptor antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Amphetamines and cocaine does what to schizophrenia why

A

Worsens schizophrenia cause they increase the level of dopamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

LSD - lysergic acid dietylamide acts on what type of receptors

A

Serotonin receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What gene is associated with schizophrenia

A

Neuregulin 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Chlopromazine
Promazine
Thioridazine
Fluohenazune

This are example of what drugs

A

Antipsychotic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Clozapine is what generation of drugs in antipsychotics

A

2nd generation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Risperidone and clozapine are what class of antipsychotics

A

Atypical antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Risperidone mechanism of action in schizophrenia is

A

Inhibiting D2 norepinephrine and serotonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Clozapine mechanism of action in schizophrenia is

A

Block of D2 and serotonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Atypical new Generation antipsychotic drugs include

A

Riseperidone
Clozapine
Sertidole
Ziprasidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly