Pharm 4 - Pharmacokinetics

Question 1

What is the principle of first order kinetics?

Answer 1

Amount of drug clearance is at a rate proportional to the conc of drug remaining in the body

CL = V x k

Question 2

Are most drugs first order or zero order?

Answer 2

First

Question 3

What does zero order kinetics imply?

Answer 3

The amount of drug decreases at a rate independent of the drug conc in the body

CL = time x k

Question 4

If a saturable metabolic process is present, first or zero order?

Answer 4

Zero