peptic ulcer disease Flashcards
peptic ulcer disease
refers to a breakdown in the gastric mucosa of 3mm in size
what ulcers typically produce gnawing or burning pain located in the abdomen between the breastbone and the navel
duodenal ulcers
what ulcers are highly associated with smoking
duodenal ulcers
what ulcers are associated with stress, infections, and use of NSAIDS
gastric ulcers
your patient presents with pain after eating and vomiting, they mention that they have also lost a significant amount of weight - what do you think is wrong
patient has gastric ulcers
why should one take precaution when taking nsaids with peptic ulcer disease
since nsaids reduce pain, they will mask the pain of peptic ulcers disease
what are the four main drug classes are used for the pharmacological management of peptic ulcer disease
anacids, antimicrobials, histamine h2 receptor antagonist and proton pump inhibitors
what is the role of antacids
neutralize gastric acid and decrease pepsin production in the stomach
what works to neutralize gastric acid and decrease pepsin production in the stomach
antacids
why can antacids alter the rate of absorption
because of the shift in pH
antimicrobials
are prescribed to eradicate the h.pylori infection
are prescribed to eradicate the h.pylori infection
antimicrobials
what can you co-administer the antimicrobials
you can co-administer with a proton pump inhibitor or a histamine H2 receptor
histamine h2 receptor antagonists
decrease gastric acid production and secretion, increases pH of gastric acid and inhibits pepsin synthesis
proton pump inhibitors
strong inhibitors of gastric acid secretion
