drugs for pulmoneary disorders - asthma

Question 1

how do our lungs brichodialte

Answer 1

sympathetic input to the lungs, the beta-2 adrenergic receptrors are stimulated relaxing the bronchioles, increasing the dialation

Question 2

what are the causes of asthama

Answer 2

air pollutants, allergien, chemicals, food, respiratory infections, stress

Question 3

air pollutants, allergens, chemicals , food, respiratory infections are all causes of what

Answer 3

asthma

Question 4

what can trigger asthma attacks

Answer 4

aspirin, ibuprofen

Question 5

what are the two main therapeutic strategies for asthma

Answer 5

they have relievers and controllers

Question 6

what is a reliever

Answer 6

this is a medication that terminate the attack

Question 7

what medications are relievers

Answer 7

beta adrenergic agonists and muscarinic antagonist

Question 8

what are controllers

Answer 8

these are medications that prevent the attack

Question 9

what medications are considered controllers

Answer 9

glucocorticoids, long acting beta adrenergic agonists, leukotriene antagonists and lipooxygenase inhibtiors

Question 10

what are the chemical mediators of asthma

Answer 10

histamine and leukotrienes

Question 11

where does histamine come from

Answer 11

mast cells

Question 12

what forms ige antibodies

Answer 12

histamine

Question 13

what is a short acting beta adregenrgic agonist good for

Answer 13

it is good for relieving the effects

Question 14

what is a long acting beta2-adrenergic agoist good for

Answer 14

controlling the attack, making sure a new one doesnt come

Question 15

adverse effects of beta2 adrenergic agonists

Answer 15

tremor and atchycardia

Question 16

what do muscarinic antagonists do

Answer 16

they block the muscarinic receptors in the smooth muscle of the bricnhi

Question 17

what work to block the muscarinic receptors in the smooth muscle and bronchi

Answer 17

muscarinic antagonists

Question 18

when are muscarinic antagonists most commonly used

Answer 18

in pt that smoke weed and have copd

Question 19

what can musacarinic antagonists be combined with

Answer 19

SABA

Question 20

glucocorticoids and asthma

Answer 20

they inhibit the syntehsis of COX -2 directly inhibiting the transcription factor

Question 21

what inhibit COX2 and the trsnsciption factor

Answer 21

glucocorticoids

Question 22

what is not n effective therapy for people with asthma attacks

Answer 22

glucocorticoids

Question 23

what are some adverse effects for high dose gluccocorticoides

Answer 23

adrenal insufficiency

Question 24

what are some adverse effects of low dose glucocorticoids

Answer 24

throat irritation, orAL candidiasis

Question 25

is glucocorticoids a contorller or reliver

Answer 25

controller

Question 26

are leukotriene receptor antagonists a controller or reliever

Answer 26

controller

Question 27

how do leukotriene receptor antagonists work

Answer 27

they competitively bind to leukotriene receptors in bronchiolar smooth muscle inudcing bronchiodilatory and immunomodulatory effects

Question 28

what competively bind to leukotrienes causing bronchidialtory and immunomodulatory effects

Answer 28

leukotriene receptor antagonists

Question 29

what are some adverse effects of leukotriene receptor antagonists

Answer 29

nausea and headache

Question 30

what can be added onto treatment if glucocorticoids are not working

Answer 30

leukotriene receptor antagonists

Question 31

what can only be used when someone is exposed predictably to a known allergen

Answer 31

mast cell stablizers

Question 32

mast cell stablizers

Answer 32

are used when there is predictable exposure to the allegeren

Question 33

going to your firends house where they have a dog that you are allergic to would be a good reason to administer what

Answer 33

mast cell stablizers

Question 34

lipoxygenase inhibitors

Answer 34

inhibit the formation of all leukotrienes

Question 35

what are lipooxyegnase inhibtiors used for

Answer 35

used for the prevention of asthma attacks, contraindictaed in clients with liver disease

Question 36

when is lipooxygenase inhibitors contraindicated

Answer 36

in pt with liver diease

Question 37

methylxanthines

Answer 37

inhibit phosphodiesterase which degardes cAMP

Question 38

what does the degradtuin if cAMP cause

Answer 38

causes calcium to be depressed, when there os no calcium, stops muscle contracyion

Question 39

iGe antibodies

Answer 39

used or allergic forms of asthma

Question 40

what reduces the production of IgE, down regulates iGe receptors, and significant mast cell stablizing effects

Answer 40

IgE anitbodies

Question 41

adverse effects IgE antibodies

Answer 41

pain, dizzness, fatigue, skin rask, anphylaxis