drugs for mood disorders

Question 1

3 classes of NT

Answer 1

small molecule, neuro peptides, NT gases

Question 2

small molecule NT

Answer 2

dopamine

Question 3

neuropeptide

Answer 3

substance p

Question 4

NT gases

Answer 4

NO

Question 5

NT important in memory

Answer 5

acetylcholine

Question 6

monoamines

Answer 6

dopamine, NE, E, serotonin

Question 7

dopamine, serotonin, NE, E are what

Answer 7

monoamides

Question 8

what system maintains emotional tone

Answer 8

noreadrenegric system

Question 9

what NT is in the noreadrenergic system

Answer 9

NE

Question 10

serotinergic system maintains what

Answer 10

maintains sleep wake cycle, emotional tone, and sensory perceptions

Question 11

maintains sleep wake cycle, emotional tone, and sensory perceptions

Answer 11

serotonergic system

Question 12

noradrenergic and serotonin system are metablozied by what

Answer 12

MAO enzyme

Question 13

§ Lack of energy
§ Sleep disturbances
§ Abnormal eating patterns
§ Feelings of despair, guilt or hopelessness
§ Most common mental health disorder of older adults
§ Encompasses physical, emotional, cognitive and social factors
are symtpoms of what

Answer 13

major depressive disorder

Question 14

biological cause and family history can be linked to what mood disorder

Answer 14

major depressive

Question 15

short lasting, often reactive as a result of a circumstance is what

Answer 15

situational depression

Question 16

what depression presents 2 weeks to 6 months after childbirth

Answer 16

postpartum

Question 17

what disorder is associated with dark winter months and lower levels of natural light

Answer 17

seasonal affective disorder

Question 18

antidepressant drugs

Answer 18

are used to treat depression by enhancing mood

Question 19

what is effective in treating both the psychological and physical signs of pain

Answer 19

antidepressants

Question 20

how do antidepressants exert their effects

Answer 20

through actions on dopamine, serotonin, and NE

Question 21

what block the enzymatic breakdown of NE and slow the reuptake of serotonin and norepinephrine

Answer 21

antidepressants

Question 22

SSRIS

Answer 22

inhibit serotonin reuptake into the presynaptic neuron

Question 23

what have no affinity for histamine, alpha adrenergic or muscarinic receptors - shows a narrow affinity

Answer 23

ssris

Question 24

what is the prefered drug class for depression

Answer 24

ssris

Question 25

why should the discontinuation of SSRIS be gradual?

Answer 25

to avoid withdrawl affects such as nausea, dizziness, anxiety, tremor, palpitations

Question 26

what is serotonin syndrome

Answer 26

this is associated with extreme increases in serotonin levels

Question 27

how does serotonin syndrome happen

Answer 27

caused by the co-adminsitration of drugs that cause an increase in serotonin

Question 28

SSRIS and MAOS can cause what

Answer 28

drug drug can cause serotonin syndrome

Question 29

SSRIS and TCAs

Answer 29

drug drug can cause SES

Question 30

SSRIS and lithium

Answer 30

can cause ses

Question 31

ssris and st. johns wart.

Answer 31

can cause ses

Question 32

MDMA and SSRIS

Answer 32

can cause ses

Question 33

SSRIS and fentanyl

Answer 33

can cause ses

Question 34

SNRIS

Answer 34

inhibit the reuptake of serotonin and NE to elevate mood

Question 35

what inhibit the reuptake of serotonin and NE to enhance mood

Answer 35

SNRIS

Question 36

what may increase the risk of post partum hemorrhage

Answer 36

SNRIS

Question 37

NDRIS

Answer 37

inhibit dopamine and epinephrine reuptake

Question 38

what drug is contraindicated in those with seizure disorders

Answer 38

NDRIS

Question 39

tricyclic antidepressants

Answer 39

inhibit NE, 5-HT and DA reuptake into the presynaptic neuron, increasing NE, 5HT and DA levels in the synapse

Question 40

inhibit NE, 5-HT and DA reuptake into the presynaptic neuron, increasing NE, 5HT and DA levels in the synapse

Answer 40

tricyclic antidepressants

Question 41

what antidepressant shows delay in efficacy, and has an affinity for histaminergic, muscarinic and a1 adrenergic receptors

Answer 41

tricyclic antidepressants

Question 42

monoamine oxidase inhibitor drugs (MAO(S)

Answer 42

deaminates DA, NE, and 5HT, inhibits MAO enzyme increasing monoamine levels

Question 43

what deaminates DA, NE, and 5HT, inhibits MAO enzyme increasing monoamine levels

Answer 43

monoamine enzyme inhibitors

Question 44

adverse effects of MAOIS

Answer 44

orthostatic hypotension, headache, insomnia, and diarrhea

Question 45

what is a hypertensive crisis assocated with

Answer 45

serotonin syndrome and elevated levels of tyramine

Question 46

what is associated with SES and elevated levels of tyramine

Answer 46

hypertensive crisis

Question 47

mood stabilizer - lithium

Answer 47

inhibits the synthesis of POP, decreasing the generation of IP3 and DAG

Question 48

what inhibits the synthesis of POP, decreasing the generation of IP3 and DAG

Answer 48

lithium

Question 49

what can be co-administered with litium

Answer 49

antidepressants and benzo

Question 50

lithium toxicity can cause what

Answer 50

muscle weakness, lack of coordination, vomiting, diarrhea, tremor, twitching, lethargy, mental confusion, polyuria

Question 51

muscle weakness, lack of coordination, vomiting, diarrhea, tremor, twitching, lethargy, mental confusion, polyuria are all symptoms of what

Answer 51

lithium toxicity

Question 52

why must someone only take lithium at night

Answer 52

to protect the kidneys

Question 53

antiseizure drugs adverse effects

Answer 53

dizziness, drowsiness, headache, nausea, blurred vision, sedation