Pathways of the Pulp Flashcards
Fluid movement within dentinal tubules can stimulate sharp, quickly reversible dental pain. What nerve fibers are responsible for this sensation?
Chapter 1: Diagnosis
A-delta nerve fibers
What nerve fibers produce an intense, slow, dull pain that can manifest as referred pain?
Chapter 1: Diagnosis
pulpal C fibers
What is the definition of spatial resolution?
Chapter 2: Radiographic Interpretation
the ability to display two objects that are close to each other as two separate entities
What is the definition of contrast resolution?
Chapter 2: Radiographic Interpretation
The ability to differentiate between areas on the image based on density
Endodontics require high-contrast resolution
What are the advantages of CBCT over multidector CT?
Chapter 2: Radiographic Interpretation
Faster, low-dose, low-cost, high-contrast images
High resolution isotropic images
What is a voxel?
Chapter 2: Radiographic Interpretation
cuboidal elements that constitute a 3D volume unlike pixels which are 2D
MDCT obtain pixels while CBCT obtains voxels
Does CBCT have lower or higher kV and mA exposure parameters than MDCT?
Chapter 2: Radiographic Interpretation
Lower
True or false: the smaller the voxel size the higher the spatial resolution
Chapter 2: Radiographic Interpretation
True
What is the maximum voxel size that should be used for endodontic imaging?
Chapter 2: Radiographic Interpretation
0.2mm
What percent mineral content loss is needed for radiolucent regions to be visualized on conventional radiographs?
Chapter 2: Radiographic Interpretation
30-40%
Planar based radiographs overestimate or underestimate success of endodontic treatment as compared to CBCT?
Chapter 2: Radiographic Interpretation
Overestimate success of endodontic treatment
What three characteristics must be present for a diagnosis of Medication Related Osteonecrosis of the Jaws (MRONJ)? (American
Association of Oral and Maxillofacial Surgeons: Position paper
on Bisphosphonate-Related Osteonecrosis of the Jaw)
Chapter 3: Case Selection and Treatment Planning
- Current or previous treatment with an antiresorptive drug
such as a bisphosphonate or an antiangiogenic drug (e.g.,
sunitinib [Sutent], sorafenib [Nexavar], bevacizumab
(Avastin), or sirolimus (Rapamune) - Exposed, necrotic bone in the maxillofacial region that has
persisted for more than 8 weeks - No history of radiation therapy to the jaws
What factors increase the risk of developing osteonecrosis of the jaw while recieving bisphosphanotes?
Chapter 3: Case Selection and Treatment Planning
history of taking bisphosphonates, especially intravenous (IV) formulations
previous history of cancer
history of a traumatic dental procedure
hx of chronic corticosteroid use
hx of diabetes
human only: hx of smoking, patient more than 65 years old
Which of the following is most correct regarding development of bisphosphonate-associated osteonecrosis?
A. The maxilla is more commonly affected than the mandible
B. 40% of cases are preceded by a dental procedure
C. patients with skeletal multiple myeloma and metastatic carcinoma recieving IV bisphosphonates comprise 94% of published MRONJ cases.
D. Patients less than 65 years old are at an increased risk
Chapter 3: Case Selection and Treatment Planning
C. patients with skeletal multiple myeloma and metastatic carcinoma recieving IV bisphosphonates comprise 94% of published MRONJ cases.
A. The mandible is more commonly affected than the maxilla (2:1 ratio)
B. 60% of cases are preceded by a dental procedure
D. Patients > 65 yro are at an increased risk
In what percent of cases are accessory canals found in the apical third of the root, the middle third and the cervical third?
Chapter 5: Tooth Morphology, Isolation and Access
Apical third 74%
Middle third 11%
Cervical third 15%
What is the definition of elastic limit in regards to endodontic instruments?
Ch 8
Maximal strain that allows a file to return to original dimensions
If you have a K file size #25 file with #.02 taper,
what mm distance is from D1 to D16 in the image, and what size in mm is the tip of the file?
What is the diameter at D16?
Distance: 0.32 mm
Tip: 0.25mm
Diameter: 0.57mm
What is the flute surface of an endodontic file?
Ch 8
Groove in the working surface that collects soft tissue and dentin from the walls, collects the dentin
What is the leading edge of an endodontic file?
What is the rake angle?
Leading edge: Surface with greatest diameter that follows the groove as it rotates – cuts the dentin
Rake angle: The angle formed by the leading edge and radius of file – Positive supposedly cuts; Negative supposedly scrapes
What is the helix angle of an endodontic file?
CH 8
The angle the cutting-edge forms with the long axis of file. Defines the type of file and how it is used
Define the order and direction of shaping the canal with each technique:
Step-back
Step-down
Crown-down
Ch 8
Step-back: Apical to coronal direction, taper canal
Step-down: Coronal pre-flaring before cleaning apically, WL before pre-flare
Crown-down: Coronal pre-flaring before cleaning apically, WL after pre-flare
What is the minimum concentration of NaOCl needed for pulp dissolution?
Ch 8
1 %
Which of the following properties of bleach leads to oxidizing pulpal tissue?
A. Saponification reaction
B. Neutralization reaction
C. Hypochlorous acid formation
D. Solvent action
Ch 8
C. Hypochlorous acid formation
Saponification reaction: Acts as an organic and fat solvent. Reduces the surface tension of the remaining solution.
Neutralization reaction: Neutralizes amino acids by forming water and salt. The pH is reduced.
Hypochlorous acid formation: Chlorine dissolves in water and it is in contact with organic matter: it forms hypochlorous acid. It is a weak acid that acts as an oxidizer.
Solvent action: Sodium hypochlorite also acts as a solvent, releasing chlorine that combines with protein amino groups (NH) to form chloramines (chloramination reaction). Chloramines impede cell metabolism and inhibits essential bacterial enzymes
What property of bleach makes it antimicrobial?
Ch8
High pH (>11)
The high pH interferes in cytoplasmic membrane integrity due to irreversible enzymatic inhibition, biosynthetic alterations in cellular metabolism, and phospholipid degradation observed in lipidic peroxidation.
What is the MOA of EDTA?
Ch 8
MOA: demineralizing chelating agent
Which of the following matches the material type and mechanism of action for GuttaFlow2 as a sealant?
A. Salicylate, Chelation
B. Silicone, Polymerization
C. Tricalcium silicate, Hydration
D. Salicylate, Ionomer formation
Ch 8
B. Silicone, Polymerization
Polymer formation by radical polymerization: Generation of a free radical monomer units results in polymers formation by the successive addition of free-radical building blocks
What is the term used to describe the histologic appearance of the coronal portion of young pulp odontoblasts?
Chp 13
The odontoblasts have a tall columnar form varying in height with nuclei staggered and not all at same level –> palisading
Appear 3-5 cells in thickness but only 1 layer
What are the layers of Dentin-Pulp Complex?
Dentin –> predentin –> odontoblast layer –> cell-poor zone –> cell-rich zone –> pulp proper
Ch 13
Are there more dentinal tubules per unit area in the root or the crown?
Ch 13
The crown
During cavity preparation what junctions in dentin are disrupted increasing dentin permeability?
Ch 13
Tight junctions
How are accessory canals formed?
By the entrapment of periodontal vessels in Hertwig’s epithelial root sheath during mineralization.
What is the most prominent cell in the pulp proper?
Ch 13
Fibroblast
Odontoblasts mainly synthesize what type of collagen?
ch 13
Type 1
What immune cells are found normally within dental pulp?
Ch 13
macrophages
dendritic cells
T lymphocytes
What type of immune cell is often found in inflamed pulp?
Ch 13
Mast cells
What is the rate of oxygen consumption of dental pulp?
Ch 13
3.2 ± 0.2 ml/min/100 g of pulp tissue
What dental materials have been shown to depress the metabolic activity of pulpal cells?
Ch 13
Eugenol
Zinc oxide and eugenol
Calcium hydroxide
silver amalgam
What primary proteogylcans are present during active primary dentinogenesis and then following eruption?
Ch 13
Dentinogenesis: Chondroitin sulfate
Tooth eruption: Hyaluronic acid
What types of collagen are present in the pulp proper?
Ch 13
Type I: thick striated fibrils thoughout pulp tissue
Type III: found in most unmineralized connective tissues
Where are Type I and Type II collagen found?
Ch 13
Type I: skin, tendon, bone, dentin, pulp
Type II: Cartilage
Where are Types IV and VII collagen found?
Ch 13
basement membranes
Where is Type V collagen found?
Ch 13
Interstitial tissues
Odontoblasts and osteoblasts synthesize what type of collagen?
Ch 13
Type 1
Fibroblasts synthesize types I, III, V, VII
Large collagen fibers are more numberous in the radicular or coronal pulp?
Ch 13
Radicular
Why pulpectomy procedures should engage pulp witha barbed broach in region of apex to remove tissue intact
What are apical deltas?
Apical deltas are multiple accessory canals that branch out from the main canal at or near the root apex.
What are furcation canals and how are they formed?
Furcation canals are accessory canals that are present in the bifurcation or trifurcation of multirooted teeth. These channels form as a result of the entrapment of periodontal vessels during the fusion of the diaphragm, which becomes the pulp chamber floor.
How are furcation lesions formed?
They are formed by pulp inflammation that communicates with the periodontium via furcation canals. Can be present without periodontal disease.
What are the functions of afferent neurons in the pulp?
Ch 13
conduct sensory impulses
What are the functions of autonomic or efferent neurons in the pulp?
Ch 13
Provide neurogenic modulation of the microcirculation, inflammatory reactions, perhaps regulate dentinogenesis
What is the path of symphathetic innervation of teeth from central to peripheral?
Ch 13
Superior cervical ganglion
Internal carotid nerve
Trigeminal nerve
Maxillary and mandibular division of trigeminal nerve
What type of A fibers compose 90% of dental pulp A fibers?
Ch 13
A-delta fibers
Function: Pain, temperature, touch
What are the characteristics and functions of A-delta fibers?
Ch 13
Myelinated
Function: pain, temperature, touch
Compose 90% of dental pulp A fibers
Located in periphery of pulp and penetrate the inner part of dentin
What are the characteristics and functions of C fibers?
Ch 13
Unmyelinated
Function: pain
Located in deeper part of pulp proper
What are the pain characteristics and stimulation thresholds of A-delta and C fibers respectively?
Ch 13
A-delta: sharp and pricking, stimulation threshold relatively low
C fibers: burning and aching, less bearable than A-delta fiber sensations, stimulation threshold realtively high, usually associated with tissue injury
What is the resting pulpal blood flow?
Ch 13
0.15 to 0.60 ml/min/g tissue
What is the consensus regarding the presence or absence of lymphatics in dental pulp?
Ch 13
Lymphatics have not consistently been demonstrated to be present in dental pulp
What inflammatory cytokines are elevated in inflamed pulp?
Ch 13
IL-1 and TNF-alpha
What is the definition of primary dentin?
Ch 13
The regular tubular dentin formed before eruption including mantle dentin
What is the definition of secondary dentin?
Ch 13
Regular circumferential dentin formed after tooth eruption
its tubules remain continuous with that of primary dentin
secondary dentin responsible for decreasing pulp width throughout life of tooth
What is the definition of tertiary dentin?
Ch 13
Irregular dentin that is formed in response to abnormal to abnormal stimuli such as excess wear, cavity preparation, restorative material, caries
What is the name of focal tertiary dentin formed by the original odontoblasts that made secondary dentin?
Ch 13
Reactionary dentin
What are the three anatomic and histological landmarks in the apical region of the root?
The apical constriction, the cementodentinal junction, and the apical foramen
What is the cementodentinal junction (CDJ)?
Histologically - where the cementum and dentin meet in the root canal. It is NOT synonymous with the apical foramen or apical constriction.
What is the name of the tertiary dentin that forms if the original odontoblasts are destroyed?
Ch 13
Reparative dentin
Tubules not continuous with those of secondary dentin, more irregular, less tubular
What can cause destruction of primary odontoblasts?
ch 13
Cutting cavity preparations dry
Bacterial products like LPS from deep carious lesions
mechanical exposure of pulps
What is the apical foramen (AF)?
The circumference or rounded edge, like a funnel or crater that differentiates the termination of the cemental canal from the exterior surface of the root.