Pathogens and the Host Flashcards

1
Q

What are the 2 important virulence factors when referring to bacterial pathogenesis

A
  • Invasiveness

- Toxins

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2
Q

What are the 4 aspects of invasiveness?

A
  • Necrotising fasciitis
  • Cellulitis
  • Connective tissue breakdown
  • Fibrinolysis
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3
Q

What are the 3 types of toxins released by some bacteria

A
  • Exotoxins
  • Enterotoxins
  • Endotoxins
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4
Q

Where are exotoxins released?

A

Extracellularly

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5
Q

What are enterotoxins?

A

Exotoxins which act on the GI tract

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6
Q

What are endotoxins?

A

Structural parts of the gram negative cell wall

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7
Q

What are the 3 features of viral pathogenesis?

A
  • Cell destruction following infection
  • Virus induced changes to gene expression
  • Immunopathogenic disease
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8
Q

What is a disease that causes cell destruction and which cells do they destroy?

A
  • HIV

- Destroy T4+ cells

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9
Q

What is a disease that alters gene expression to cause a tumour?

A
  • HPV-1
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10
Q

What is an example of an immunopathogenic disease?

A
  • Influenza A
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