Pathogens and the Host Flashcards
1
Q
What are the 2 important virulence factors when referring to bacterial pathogenesis
A
- Invasiveness
- Toxins
2
Q
What are the 4 aspects of invasiveness?
A
- Necrotising fasciitis
- Cellulitis
- Connective tissue breakdown
- Fibrinolysis
3
Q
What are the 3 types of toxins released by some bacteria
A
- Exotoxins
- Enterotoxins
- Endotoxins
4
Q
Where are exotoxins released?
A
Extracellularly
5
Q
What are enterotoxins?
A
Exotoxins which act on the GI tract
6
Q
What are endotoxins?
A
Structural parts of the gram negative cell wall
7
Q
What are the 3 features of viral pathogenesis?
A
- Cell destruction following infection
- Virus induced changes to gene expression
- Immunopathogenic disease
8
Q
What is a disease that causes cell destruction and which cells do they destroy?
A
- HIV
- Destroy T4+ cells
9
Q
What is a disease that alters gene expression to cause a tumour?
A
- HPV-1
10
Q
What is an example of an immunopathogenic disease?
A
- Influenza A
