Cancer Genes and Biomarkers Flashcards
1
Q
What is KRAS a biomarker of?
A
Colorectal cancer
2
Q
What is BRAF a biomarker of?
A
Melanoma
3
Q
What cancer do mutations in the HER 1 & 2 genes lead to?
A
Breast cancer
4
Q
What do mutations in the BRCA 1 & 2 genes have the potential to lead to?
A
- Breast cancer
- Ovarian cancer
5
Q
What are HER and BRCA examples of?
A
Oncogenes
6
Q
What does FAP stand for?
A
Familial Adenomatous Polyposis
7
Q
How is the FAP gene developed?
A
Hereditary
8
Q
What does the presence of the FAP gene cause?
A
Polyps in the colon
9
Q
What does the presence of the FAP gene increase the chances of?
A
Colorectal cancer
10
Q
What is the BGFR biomarker a biomarker of?
A
Lung cancer
11
Q
What is AFP a biomarker of?
A
Hepatic cancer + testicular teratoma
12
Q
What can you treat hormone sensitive breast cancer with?
A
Tamoxifen
