Mendelian Inheritance Flashcards
In autosomal dominant, what is the distribution between generations?
Every generation affected
In autosomal dominant, what is the distribution between sexes?
Equal
In autosomal dominant, what is the proportion of which sex transmits the disease more?
50:50
What are the chances of inheriting the disease In autosomal dominant?
50%
In autosomal recessive, what is the pattern of inheritance between generations?
Generations “skipped”
In autosomal recessive, what is the distribution between the sexes?
Equal
What do both parents have to be in order for offspring to be affected?
Both carriers or both affected
Who is more affected by X linked recessive?
Males
How is X linked recessive normally transmitted?
Through unaffected female carriers
What will be the genotype of daughters of affected men in X linked recessive?
Carriers unless mother is a carrier/affected
In X linked dominant, what pattern of disease is shown?
Both sexes affected
Who is affected more severely in X linked dominant?
Males
What will be the genotype of daughters of affected men in X linked dominant?
Affected