ANTIBIOTICS that inhibit CELL WALL synthesis - The name of the antibiotic, state its subclass and mode of action on which bacterium

Question 1

Benzylpenicillin

Answer 1

• B lactam
• Action on mostly gram positive
• Best for Neisseria Meningitidus

Question 2

Amoxicillin

Answer 2

• B lactam
• Action on gram negative and streptococci gram positive
• Good oral absorptive properties

Question 3

Ampicillan

Answer 3

• B lactam
• Action on gram negative and streptococci gram positive
• Good oral absorption

Question 4

Co-amoxiclav

Answer 4

• B lactam

- Gram negative

Question 5

Flucloxacillin

Answer 5

• B lactam

- Staphylococci

Question 6

Piperacillan

Answer 6

• B lactam
• Broad action spectrum, slightly better for gram negative
• Good anti anaerobic activity, e.g. on enterococcus faecalis

Question 7

Imipenem

Answer 7

• B lactam

- Most bacterium

Question 8

Meropenem

Answer 8

• B lactam
• Most bacterium
• Has widest spectrum

Question 9

Teicoplanin

Answer 9

• Glycopeptide
• Gram positive ONLY
• Inhibit peptidoglycan precursor production
• Can’t infiltrate gram negative cell wall

Question 10

Vancomycin

Answer 10

• Glycopeptide
• Gram positive ONLY
• Inhibit peptidoglycan precursor production
• Can’t infiltrate gram negative cell wall

Question 11

Cephalosporins

Answer 11

• Cephalosporins

- Gram negative and positive