Parkinson's Disease Flashcards
What is the etiology of Parkinson’s
Idiopathic
What does Parkinson’s eventually lead to?
Disability
What is the patho of Parkinson’s?
Destruction of pigmented neuronal cells in the substantia nigra in the basal ganglia -> decreased dopamine levels -> degeneration of the dopaminergic pathway -> imbalance of excitatory (ach) and inhibitory (dopamine) neurotransmitters -> impairment of extra pyramidal reacts controlling complex body movements -> tremors, rigidity, bradykinesia, postural changes
How is Parkinson’s diagnosed?
Hx
Presence of 2/4 Cardinal signs
What are mnft of Parkinson’s
Tremors
Rigidity
Bradykinesia
Postural inability
How is Parkinson’s treated?
symptom management
No actual treatment however there are medications that help the manifest ions
Levodopa
Antivirals
Dopamine agonists
Mao inhibitors (inhibit breakdown of dopamine)
What is Parkinson’s?
A slowly professing neurological movement disorder