Parkinson's Disease Flashcards

1
Q

What is the etiology of Parkinson’s

A

Idiopathic

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2
Q

What does Parkinson’s eventually lead to?

A

Disability

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3
Q

What is the patho of Parkinson’s?

A

Destruction of pigmented neuronal cells in the substantia nigra in the basal ganglia -> decreased dopamine levels -> degeneration of the dopaminergic pathway -> imbalance of excitatory (ach) and inhibitory (dopamine) neurotransmitters -> impairment of extra pyramidal reacts controlling complex body movements -> tremors, rigidity, bradykinesia, postural changes

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4
Q

How is Parkinson’s diagnosed?

A

Hx

Presence of 2/4 Cardinal signs

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5
Q

What are mnft of Parkinson’s

A

Tremors
Rigidity
Bradykinesia
Postural inability

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6
Q

How is Parkinson’s treated?

A

symptom management
No actual treatment however there are medications that help the manifest ions
Levodopa
Antivirals
Dopamine agonists
Mao inhibitors (inhibit breakdown of dopamine)

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7
Q

What is Parkinson’s?

A

A slowly professing neurological movement disorder

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