Leukemia Flashcards

1
Q

Who is leukemia most common in?

A

Children and young adults

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2
Q

What is leukemia classified as?

A

Acute and chronic lymphocytic leukemia or acute and chronic myelogenous leukemia

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3
Q

In acute forms of leukemia what cells tend to be affected?

A

Immature blast cells

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4
Q

In chronic leukemia which cells are often affected?

A

Mature cells

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5
Q

Is acute leukemia often aggressive or not as aggressive?

A

Aggressive

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6
Q

Is chronic leukemia aggressive or not as aggressive?

A

Not as aggressive

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7
Q

What cells are affected in myelogenous leukemia?

A

Monocytes and granulocytes

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8
Q

What is the etiology of leukemia?

A

It is due to mutated genes, but exact cause is idiopathic

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9
Q

What are risk factors for leukemia?

A

Genetic predisposition, excessive radiation from X-rays, t-cell leukemia virus, and immunodeficiency

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10
Q

Is non-malignant blood cel production affected in leukemia? If so, why?

A

Yes. Because there is decreased space in the bond marrow and malignant cells are taking up all of the resources.

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11
Q

In leukemia, what occurs as a result of improper blood cell production in the bone marrow?

A

An impaired immune response and a decreased oxygen supply to the tissues because of less red blood cells being produced

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12
Q

What are manifestations of leukemia?

A
Anemia 
Thrombocytopenia 
Leukopenia
Bleeding gums 
Fever 
Generalized pain
Fatigue, weakness, bruising 
Recurrent infection
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13
Q

What is the treatment for leukemia?

A
Radiation & chemo
Blood transfusions 
Antimicrobials 
CS factors (enhance proliferation of colony cells) 
Marrow transplant
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14
Q

What is meant by induction, intensification and maintenance when speaking of treatment for leukemia? And how long does this happen for?

A

Inducing remission, intensifying the remission and maintaining the remission. This lasts for 12-24 months

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15
Q

Where are malignant cells found in leukaemia?

A

Present in circulation and may infiltrate tissues

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