Coronary Artery Disease Flashcards

1
Q

True or false: CAD disease is not a major cause of death

A

False

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2
Q

What is the main cause of CAD?

A

Atherosclerosis

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3
Q

What types of ACS are there?

A

Unstable angina, MI, and sudden cardiac death

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4
Q

What types of chronic ischemic heart disease are there?

A

Stable angina and congestive heart failure

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5
Q

What is a manifestation of coronary artery disease?

A

Angina

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6
Q

What causes angina pectoris?

A

Atherosclerosis mainly, vasospasms, and thrombosis

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7
Q

What is the patho physiology of angina?

A

Inadequate perfusion leads to ischemia which leads to chest pain

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8
Q

What are manifestations of angina?

A

Chest pain which is triggered on exertion

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9
Q

What are the characteristics of stable angina?

A

It deals with a fixed plaque which impedes perfusion and causes transient pain from the ischemia

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10
Q

What is transient pain?

A

Pain that can be relieved when the trigger is taken away

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11
Q

True or false: stable angina is triggered by exertion

A

True

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12
Q

What are the characteristics of unstable angina?

A

Deals with an unstable plaque that can burst, and if it bursts a thrombus will form as platelets aggregate.

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13
Q

What do platelets release when the aggregate on the atherosclerotic plaque and what results from it?

A

Prostaglandins which causes a vasospasm

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14
Q

True or false: pain in unstable angina occurs only on exertion.

A

False. Pain can occur nocturnally and at rest too

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15
Q

What is variant/vasospastic angina?

A

No atherosclerosis is present, however vasospasm occurs in the artery causing ischemia and chest pain

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16
Q

When does variant/vasospastic angina occur?

A

Nocturnally and at rest

17
Q

What are manifestations of angina?

A

Squeezing or burning chest pain, sometimes accidentally thought to be heart burn or indigestion

18
Q

What subcategories of CAD are there?

A

Acute coronary syndromes (CAS) and chronic ischemic heart disease

19
Q

What is the treatment for angina?

A

Decrease activity, nitro-glycerin

20
Q

What can be prevented if you treat angina?

A

MI

21
Q

What is a myocardial infarction based on an ECG?

A

S-T Elevated MI STEMI

22
Q

Define the characteristics of a MI

A

It is the end point of CAD, it is life threatening and it has an acute onset

23
Q

What is the etiology of a MI?

A

Mainly atherosclerosis, a hemorrhage or a coronary artery spasm (any artery in the coronary circuit)

24
Q

What is the Patho of a MI?

A

Atherosclerosis leads to a complicated lesion which results in ischemia, wish ischemia anaerobic respiration happens and then metabolic acidosis which causes arrhythmias leaving the heart unable to pump properly

25
Q

What five factors determine how large an infarct is?

A

Affected vessel (how much tissue is affected)
Extent of occlusion
Duration of ischemia
Metabolic status of the heart (HR, BP, rhythm)
Collateral circulation

26
Q

What two types of MIs are there?

A

Subendocardial infarct (NSTEMI) and a transmural infarct (STEMI)

27
Q

What part of the heart is affected in a subendocardial infarct?

A

Inner 1/2 to 1/3 of the ventricle wall

28
Q

What part of the heart is affected in a transmural infarct?

A

Entire ventricle wall

29
Q

Which type of MI is more serious?

A

Transmural

30
Q

Which vessels are occluded to cause a subendocardial infarct?

A

Distal vessels, not a main artery

31
Q

Which vessels are occluded to cause a transmural infarct?

A

One main artery, it is a proximal occlusion

32
Q

What are manifestations of an MI?

A

Severe chest pain that radiates into the jaw, neck or left arm
Anxiety
Tachycardia
Nausea and vomiting

33
Q

How can you diagnose an MI?

A

ECG
Angiogram
Blood work

34
Q

What do you look for in blood work to diagnose an MI?

A

Troponin I and T
Myoglobin (carries O2 in heart muscle)
CKmb

35
Q

Treatment of an MI (STAT tx)

A

STAT medical attention
Thrombolytic & anti coag & anti arrhythmic used at same time
O2 for hypoxia
Opioids for pain

36
Q

Once stabilized what are the treatments for an MI?

A

IV diuretic
Negative inotrope
Vasodilator
ALL DEC STRESS ON HEART

Revascularization surgery (angioplasty if minimal or bypass if angioplasty is not possible)