Lymphoma

Question 1

Which lymphoma has the presence of reed stern berg cells?

Answer 1

Hodgkin

Question 2

Where does the cancer originate from and how does it spread in Hoskin lymphoma?

Answer 2

Arises in a single lymph node and then spreads from node to node

Question 3

Can Hodgkin lymphoma invade other tissues in the body not just lymph nodes?

Answer 3

Yes

Question 4

Where does non Hodgkin lymphoma arise? How does it spread?

Answer 4

It arises in multiple areas of the body and invades tissues within the body

Question 5

Is the bone marrow involved in both NHL and HL?

Answer 5

Yes

Question 6

What are “B” symptoms of NHL and HL?

Answer 6

Fever
Night sweats
Weight loss

Question 7

Which form of lymphoma arises from both t or B cells?

Answer 7

NHL

Question 8

When the T cells are differentiating, where do genetic mutations in NHL commonly occur?

Answer 8

Paracortical region of the lymph node

Question 9

What cell is more common to have a NHL arise from?

Answer 9

B cell

Question 10

What are some risk factors for NHL?(3)

Answer 10

Immunodeficiency (primary or secdonary)
EBV
HIV

Question 11

What are some treatments for NHL?(4)

Answer 11

Monoclonal antibody with chemotherapy treatment
Radiation for earlier stages
Bone marrow transplant
Peripheral stem cell transplant

Question 12

What cells are mutated in HL?

Answer 12

B cells

Question 13

Risk factors for HL (3)

Answer 13

Specific age groups (15-40 or >55)
EBV
HIV

Question 14

Why are reed stern berg cells created in HL?

Answer 14

Genetic mutation in the differentiation of B cells in the germinal or postgerminal areas of a lymph node

Question 15

What 4 categories can HL be broken into?

Answer 15

Lymphocytic rich
Lymphocytic depleted
Modular sclerosis
Mixed cellularity

Question 16

What are some treatments for HL?

Answer 16

Radiation in earlier stages

Combo therapy in later and more aggressive stages

Question 17

What two categories can lymphomas be broken into?

Answer 17

Hodgkin

Non Hodgkin