parasympathetic nervous system Flashcards
atropine poisoning: identify the signs and symptoms of atropine poisoning and explain how it may be treated
1
Q
effect of atropine
A
muscarinic receptor antagonist
2
Q
what drugs are used to treat an atropine overdose
A
inhibit atropine, increase ACh, or decrease AChE activity: physostigmine (anti-cholinesterase so reversible indirect muscarinic receptor agonist), bethanechol (stable ACh so competes)
3
Q
other parasympatholytic (drug that reduces PSNS activity) and how it works
A
botulinum toxin (Botox; cleaves and inhibits SNARE complex in ACh production and release, so prevents ACh exocytosis, causing paralysis of skeletal muscle)
