parasympathetic nervous system Flashcards
anticholinesterase poisoning: recognise the signs and symptoms of anticholinesterase poisoning and explain how it may be treated
1
Q
organophosphate poisoning: what causes severe toxicity
A
accidental exposure to organophosphates in insecticides, or nerve agents
2
Q
effect of organophosphate poisoning
A
increased muscarinic activity, CNS excitation (seizures), depolarising neuromuscular block; highly lipid soluble so easily accesses systemic circulation
3
Q
treatment of organophosphate poisoning
A
atropine (iv) to block muscarinic receptors, artificial respiration, pralidoxime (iv) to act at nicotinic and muscarinic receptors to rescue AChE from block (reverse block within first couple of hours, otherwise irreversible)
