general autonomic nervous system pharmacology topic Flashcards
autonomic target organs: identify the principal target organs of (a) the sympathetic nervous system and (b) the parasympathetic nervous system and describe how each responds to autonomic stimulation
principal efferent outputs from ANS
exocrine glands, smooth muscle, cardiac muscle, metabolism, host defence
dominant ANS branch of heart at rest
parasympathetic
effect of SNS and PSNS on: eye, salivary glands, trachea and bronchioles, skin, heart, liver, GI, blood vessels, adipose, kidney, ureters and bladder
SNS: dilate pupil, PSNS: constrict pupil and ciliary muscle; SNS: thick, viscous, PSNS: copious, watery; SNS: dilates (adrenaline), PSNS: constricts; SNS: piloerection and increased sweating (cholinergic); SNS: increases rate and contractility, PSNS: decreases rate and contractility; SNS: glycogenolysis and gluconeogenesis; SNS: decreases motility and tone, causes sphincter contraction; PSNS: increases motility and tone and secretions; SNS: dilate skeletal muscle, constrict skin, mucous membranes and splanchnic area; SNS: lipolysis; SNS: increased renin secretion; SNS: relaxes detrusor, constricts trigone and sphincter; PSNS: contracts detrusor, relaxes trigone and sphincter
pharmacodynamics
what drug does to body
pharmacokinetics
what body does to drug