addiction Flashcards
reward pathways: identify the reward pathways in the brain activated by drugs of abuse
1
Q
name of central ‘reward’ pathway
A
mesolimbic dopamine system
2
Q
mesolimbic dopamine system for reward pathway (abused to cause euphoria)
A
rewarding stimulus -> cell bodies in ventral tegmental area -> project down into nucleus accumbens (ventral striatum) -> dopamine release -> feelings of reward
3
Q
how do opiates induce euphoria
A
bind to u-receptor on GABAergic neurone -> inhibit GABA release -> cell bodies in ventral tegmental area -> project down into nucleus accumbens (ventral striatum) -> dopamine release -> feelings of reward
4
Q
S33
A
S33