general autonomic nervous system pharmacology topic Flashcards
neurotransmitters: identify the transmitters released from pre- and postganglionic fibres in the sympathetic and parasympathetic nervous systems
parasympathetic innovation origin
cranial, sacral
sympathetic innovation origin
thoracic, lumbar
parasympathetic [long] pre and [short] post ganglionic neurotransmitter
acetylcholine
sympathetic [short] pre ganglionic neurotransmitter
acetylcholine
normal sympathetic [long] post ganglionic neurotransmitter
noradrenaline
what is released into bloodstream by sympathetic stimulation of adrenal medulla (only innovated by one fibre)
adrenaline and noradrenaline
when is acetylcholine used as a sympathetic post ganglionic neurotransmitter
sweat glands (secretion)
features of PSNS, pre vs post fibres
discrete, localised, little divergence, 1:1 pre vs post ganglionic
features of SNS, pre vs post fibres
coordinated response, so very divergent with up to 1:20 pre vs post ganglionic
sensory neurone in enteric nervous system
connected to mucosal chemoreceptors and stretch receptors; information relayed by submucosal and myenteric plexus via interneurones
motor neurones in enteric nervous system
release acetylcholine or substance P to contract smooth muscle or vasoactive intestinal peptide or NO to relax smooth muscle
somatic nervous system feature and neurotransmitter
one long ganglion from spinal cord to effector organ; acetylcholine