general autonomic nervous system pharmacology topic Flashcards

neurotransmitters: identify the transmitters released from pre- and postganglionic fibres in the sympathetic and parasympathetic nervous systems

1
Q

parasympathetic innovation origin

A

cranial, sacral

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2
Q

sympathetic innovation origin

A

thoracic, lumbar

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3
Q

parasympathetic [long] pre and [short] post ganglionic neurotransmitter

A

acetylcholine

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4
Q

sympathetic [short] pre ganglionic neurotransmitter

A

acetylcholine

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5
Q

normal sympathetic [long] post ganglionic neurotransmitter

A

noradrenaline

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6
Q

what is released into bloodstream by sympathetic stimulation of adrenal medulla (only innovated by one fibre)

A

adrenaline and noradrenaline

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7
Q

when is acetylcholine used as a sympathetic post ganglionic neurotransmitter

A

sweat glands (secretion)

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8
Q

features of PSNS, pre vs post fibres

A

discrete, localised, little divergence, 1:1 pre vs post ganglionic

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9
Q

features of SNS, pre vs post fibres

A

coordinated response, so very divergent with up to 1:20 pre vs post ganglionic

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10
Q

sensory neurone in enteric nervous system

A

connected to mucosal chemoreceptors and stretch receptors; information relayed by submucosal and myenteric plexus via interneurones

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11
Q

motor neurones in enteric nervous system

A

release acetylcholine or substance P to contract smooth muscle or vasoactive intestinal peptide or NO to relax smooth muscle

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12
Q

somatic nervous system feature and neurotransmitter

A

one long ganglion from spinal cord to effector organ; acetylcholine

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