Para malaria 1 Flashcards
Related to primate malaria parasite (3)
P. vivax
P. malariae
P. ovale
related to avian malaria parasites
P. falciparum
long tailed macaques malaria parasite
P. knowlesi
TRANSMISSION of MALARIA IS THROUGH THE BITE OF A ____________________________
female Anopeheles mosquito
malaria is known as ________________________ in French
Paludisme= swamp fever
Discovered Malaria n the RBCs of a patient in 1880
Charles Louis Alphonse Laveran
malaria is known as ________________________ in German
Wechselfieber= changing fever
described the asexual development called the Golgi Cycle
Camillo Golgi
Established the mode of transmission of Malaria in 1897
Ronald Ross
P. ovale was identified during _____
1922
GROUP OF PARASITES CAUSING MALARIA belongs to the genus Plasmodium (5)
Plasmodium vivax
Plasmodium ovale
Plasmodium malariae
Plasmodium falciparum
Plasmodium knowlesi
considered to be the fifth human malaria parasite has been described in humans in the Philippines and SEA
Plasmodium knowlesi
In the Philippines, principal malarial vector is the _______________________________________________
Anopheles minimus var. flavirostris
Malaria parasite requires specific __________ and ______________ to complete its life cycle
human, mosquito tissues
Lifespan of Female Anopheles mosquito
few weeks to a month
intermediate host of Malaria parasite
HUMANS
Gametocyte appearance in the circulation:
P. vivax= _____________
P. falciparum= ________________
4-5 days, 10-12 days
A person with a malaria gametocyte
Carrier or Resevoir
infective stage of Malaria for humans
Sporozoites
Process of schizogony forms ____________________
Merozoites (individual things)
Schizonts (if grouped)
the asexual reproduction of a sporozoan parasite by the multiple fission of the nucleus of the parasite followed by segmentation of the cytoplasm
Schizogony
Schizogony forms
MEROZOITES
Sporogony results in a production of ______________________________
SPOROZOITES
Sexual reproduction by multiple fission of a spore or zygote, characteristic of many sporozoans
Sporogony
Process of the malaria parasite to undergo gamete formation
GAMETOGONY
Name of gametocyte for male and female respectively
MICROGAMETOCYTE- MALE, MACROGAMETOCYTE- FEMALE
the erythrocytic cycle occurs in the ______________________
CIRCULATION
the exoerythrocytic cycle occurs in the ______________________
LIVER
Definitive host of MALARIA
MOSQUITO
The MALARIA parasite develops and multiplies inside the human host causing ____________________
periodic bouts of flu-like symptoms
infective stage of MALARIA for mosquito
GAMETOCYTE
Classical malarial paroxysms/ MALARIAL TRIAD (3)
Chills (cold stage)
Fever (Hot stage)
Sweating (Sweating stage)
symptoms of MALARIA are related to the periodic destruction of _____ and diffusion of the pigment __________
RBCs, Hemozoin
The interval of time from sporozoite injection to detection of parasites in the blood
PREPATENT PERIOD
30 MINSt
The time between sporozoite injection and the appearance of clinical symptoms
INCUBATION PERIOD/ CLINICAL IP
the sudden inappropriate feeling of coldness and apprehension
COLD PHASE
Cold phase rigor lasts for ——————
15-60 mins
Patient is hot/ flush phase begins, moreover patient has headache, palpitations, tachypnea, epigastric discomfort, thirst, nausea, vomiting
HOT PHASE
HOST PHASE LASTS FOR _____________________________
2-6 hours
HOT PHASE TEMP peaks at _____________________________
40-41 deg C
is due to the bursting of the RBCs in the body
COLD PHASE
is due to the immune response of the body
HOT PHASE
defervescence or diaphoresis- patient manifest sweating
SWEATING PHASE
SWEATING PHASE temp lower over the next ___________________
2-4 hours
TOTAL DURATION of typical malarial attack
8-12 hours
Interval between attack is determined by the length of ___________________________________
Erythrocytic Cycle
is due to the compensation of the body to the immune response of the body to the parasite
SWEATING PHASE
malaria may cause ___________ and ________________
anemia and jaundice
infection with one type of malaria, _________________________, if not properly treated may cause kidney failure, seizures, mental confusion, coma, and death
Plasmodium falciparum