Pancreatic Clinical Pathology Flashcards
what is malassimilation?
failure to take up nutrients from the digestive tract
how are lipids broken down?
lipase
bile acids
what is folate?
water-soluble B vitamin: B9
what can deficiencies or defective absorption of cobalamin (vitamin B12) cause?
anemia
CNS degeneration
how do you get cobalamin?
intake from diet: bound to proteins
what is the gold standard for detecting pancreatitis?
histopathology
what blood tests can be used to look for pancreatitis?
amylase
lipase
pancreatic lipase
what do amylases do?
break down complex carbohydrates (starch and glycogen)
what is a marked increase in serum amylase (hyperamylasemia) suggestive of?
pancreatic disease
more than mild increase
what inactivates and excretes serum lipases?
kidney
what can corticosteroids do with lipase activity?
can increases up to 5x
is lipase or amylase considered a more sensitive indicator of pancreatic necrosis?
lipase more sensitive
what can happen with liver enzymes in pancreatitis?
pancreatitis can cause increased liver enzymes and bilirubin