Pancreatic Clinical Pathology Flashcards

1
Q

what is malassimilation?

A

failure to take up nutrients from the digestive tract

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2
Q

how are lipids broken down?

A

lipase
bile acids

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3
Q

what is folate?

A

water-soluble B vitamin: B9

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4
Q

what can deficiencies or defective absorption of cobalamin (vitamin B12) cause?

A

anemia
CNS degeneration

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5
Q

how do you get cobalamin?

A

intake from diet: bound to proteins

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6
Q

what is the gold standard for detecting pancreatitis?

A

histopathology

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7
Q

what blood tests can be used to look for pancreatitis?

A

amylase
lipase
pancreatic lipase

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8
Q

what do amylases do?

A

break down complex carbohydrates (starch and glycogen)

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9
Q

what is a marked increase in serum amylase (hyperamylasemia) suggestive of?

A

pancreatic disease
more than mild increase

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10
Q

what inactivates and excretes serum lipases?

A

kidney

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11
Q

what can corticosteroids do with lipase activity?

A

can increases up to 5x

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12
Q

is lipase or amylase considered a more sensitive indicator of pancreatic necrosis?

A

lipase more sensitive

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13
Q

what can happen with liver enzymes in pancreatitis?

A

pancreatitis can cause increased liver enzymes and bilirubin

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