Other Topical Dermatologic Drugs Flashcards
acyclovir (zovirax) & penciclovir (denavir)
- used to treat HSV 1 & 2
- used to treat HPV **can cause anogenital warts
- acyclovir; pregnancy C drug
- penciclovir; pregnancy B drug
when treating with TOPICAL ANTIVIRAL DRUGS, what do we need to consider?
- doesn’t necessarily CURE these viral infections, just REDUCES HEALING TIME & PAIN
- want to wear RUBBER GLOVES during application
what are TOPICAL ANESTHETIC DRUGS used for?
- helps to REDUCE PAIN/NUMB THE SKIN
- often to treat associated pain with; INSECT BITES, SUNBURN, or POISON IVY EXPOSURE
- comes in many different forms
what are our TOPICAL ANESTHETIC DRUGS? what are some ADVERSE EFFECTS?
- EMLA; type of LIDOCAINE-PRILOCAINE COMBINATION
- ELA-MAX; LIDOCAINE used in PEDIATRICS
some adverse effects;
- itching
- nausea/vomiting
- headaches
- dizziness
what are our ANTIPSORIATIC DRUGS? (8)
- TAZAROTENE (TAZORAC)
- TAR-CONTAINING PRODUCTS
- ANTHRALIN (ANTHRA-DERM)
- CALCIPOTRIENE (DOVONEX)
- ETANERCEPT (ENBREL)
- ALEFACEPT (AMEVIVE)
- USETEKINUMAB (STELARA)
- IZEKIZUMAB (TAITZ)
tazarotene
- type of RECETPRO-SELECTIVE RETENTION
- MOA;
normalizes EPIDERMAL DIFFERENTIATION–reduces INFLAMMATORY CELLS
indications;
- used for STABLE PLAQUE PSORIASIS or MILD to MODERATE FACIAL ACNE
**is a PREGNANCY CATEGORY X DRUG; need a NEGATIVE PREGNANCY TEST 2 WEEKS PRIOR TO START
adverse effects
- skin irritation
- redness
- dryness
- photosensitivity
tar-containing products
- has ANTISEPTIC, ANTIBACTERIAL, and ANTISEBORRHEIC PROPERTIES
- helps to SOFTEN or LOOSEN SCALY or CRUSTY AREAS of the skin
- has many different forms
adverse effects;
- irritation
- skin burning
- photosensitivity
anthralin (anthra-derm)
- MOA; inhibits DNA SYNTHESIS and MITOSIS–this REDUCES psoriatic lesions
- available as ointment or cream
- applied only ONCE DAILY
- preg category C
calcipotriene (dovonex)
- type of SYNTHETIC VITAMIN D analogue
- works by BINDING TO VITAMIN D RECEPTORS; these are important in regulating skin growth & keratinocytes
- pregnancy C drug
adverse effects;
- irritation
- worsening of PSORIASIS
- dermatitis
- skin atrophy
- folliculitis
what drugs are used to treat LICE PEDICULOSIS or SCABIES?
usage of TOPICAL ECTOPARASITICIDAL DRUGS
ex.
- PERMETHRIN (ELIMITE)
- MALATHION (OVIDE)
- CROTAMITON (EURAX)
where is LICE and SCABIES typically seen?
seen often in DAYCARES or NURSING HOMEs
- can cause the BURROWING OF SKIN
- need to clean surfaces and properly rinse with hot water
benzyl alcohol 5% (ULESFIA)
- begins to SUFFOCATE LICE
spinospad (NATROBA)
can cause PARALYSIS of parasites
topical ivermectin
induces PARALYSIS and DEATH of lice
what are our TOPICAL HAIR GROWTH DRUGS?
- MINOXIDIL (ROGAINE)
- FINASTERIDE (PROPECIA) **more systemic
minoxidil (ROGAINE)
can be used for both MEN and WOMEN
- works by increased vasodilation/blood flow and increasing opening of potassium channels
finasteride (PROPECIA)
- known as a PREGNANCY CATEGORY X DRUG
- cannot CRUSH THIS DRUG – can be potential risk for pregnant women if airborne
- can cause SYSTEMIC/LOCAL EFFECTS:
tachycardia
fluid retention
weight gain
skin irritation
fluorouracil (EFUDEX)
- type of TOPICAL ANTINEOPLASTIC
- works as an ANTIMETABOLITE
- helps to treat BASAL CELL CARCINOMA or ACTINIC KERATOSIS
- often use gloved fingers/applicator for application
- can cause serious side effects;
- soreness, scaling, swelling, pain, tenderness, dermatitis, photosensitivity
what are our IMMUNOMODULATOR DRUGS?
- PIMECROLIMUS (ELIDEL)
- IMMIQUIMOD (ALDARA)
pimecrolimus (elidel)
- help to treat ATOPIC DERMATITIS
- adverse effects; MINOR SKIN IRRITATION
imiquimod (aldara)
- treats ACTINIC KERATOSIS, BASAL CELL CARCINOMA, and ANOGENITAL WARTS
- want to assess for SYSTEMIC REACTIONS and adverse reactions;
- burning, indurations, irritation, pain or bleeding
- edema, erosions, exudations, vesicles
- COUGH, URI, MS reactions
isopropyl alcohol
used before MINOR PROCEDURES - like drawing blood or giving injections
povidone-iodine (BETADINE)
- kill BACTERIA, FUNGI, and VIRUSES
- treatment of TOPICAL INFECTIONS with
- surgery
- burns
- cuts or scrapes
- minor vaginal infections
**need to assess IODINE ALLERGY – shellfish allergies *since it contains IODINE
chlorhexidine (HIBICLENS)
works by DISRUPTING BACTERIAL MEMBRANES and INHIBITS CELL WALL SYNTHESIS
- used for SURGICAL SCRUBBING or HAND-WASHING AGENT
benzalkonium chloride (ZEPHIRAN)
- type of SURFACE-ACTIVE DRUG that DENATURES the MICROORGANISM or destroys its PROTEINS
- used before SURGERY or MINOR WOUND CARE
aloe
- used for WOUND HEALING
- adverse effects;
- DIARRHEA, ABDOMINAL PAIN, DERMATITIS
DRUG INTERACTIONS
- DIGOXIN
- ANTIDYSTHYTHMICS
- DIURETICS
