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NURS 212A > Macrolides > Flashcards

Macrolides Flashcards

1
Q

mechanism of action

A
  • BACTERIOSTATIC, if conc. is high enough - can become BACTERICIDAL
  • binds to the 50S RIBOSOMAL SUBUNITS
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2
Q

indications

A
  • upper and respiratory infections
  • syphilis/lyme disease/gonorrhea
  • stimulates SMOOTH MUSCLES/GI MOBILITY for feeding tubes
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3
Q

contraindications

A

drug allergy

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4
Q

adverse effects

A
  • hepatotoxicity
  • N & V
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5
Q

interactions

A
  • drugs are very PROTEIN BOUND - can be quite heavy on the LIVER
  • prolonged drug effects; warfarin, cyclosporine, etc…
  • can reduce efficacy of oral contraceptives
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6
Q

common names

A
  • AZITHROMYCIN *longer duration
  • CLARITHROMYCIN *longer duration
  • ERYTHROMYCIN
  • FIDAXOMICIN
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NURS 212A (17 decks)

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