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Bases > Osteosarcoma y sarcoma de Windkjbd > Flashcards

Osteosarcoma y sarcoma de Windkjbd Flashcards

1
Q

¿Donde puede dar osteosarcoma?

A

1.-Mas frecuente en huesos largos
2.- centrales o medulares y periféricos

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2
Q

Lesiones en metafisis que no rompen cortical

A
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3
Q

Lesiones den diáfisis

A
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4
Q

Lesiones en metáfisis

A
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5
Q

¿Que es el osteosarcoma central?

A
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6
Q

¿Qué es el osteosarcoma de periférico?

A
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7
Q

¿Que es el osteosarcoma central convencional?
–> más del 90% = muerte

A
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8
Q

¿Que es el osteosarcoma central telangiectásico?

A

1.- en fémur distal
–>

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9
Q

¿Que es el osteosarcoma central células pequeñas ?

A

1.- Metáfisis de huesos largos
2.- el ppal dato para diferenciarlo de uno de wuiidn es la edad la localización = diáfisis

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10
Q

¿Que es el osteosarcoma central Bajo grado?

A
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11
Q

¿Que es el sindrome de RETINOBLASTOMA , LI FRAUMENI, ENFERMEDAD DE OLLIER, OSTEOBLASTOMA, PAGET Y OTRAS?

A
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12
Q

MATERIAL AMORFO FINO EOSINOFILO

A

OSTEOIDE

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13
Q

¿Qué es SARCOMA DE EWING/PNET?

A

–> alteraciones en EWS/ETS

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14
Q

cuadro clínico de SARCOMA DE EWING?
–> sistémico

A

Dolor, fiebre, pérdida de peso, Leucocitosis, SEDIMENTACIÓN ERITROCITARIA ELEVADA

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15
Q

TINCIONES DE INMUNOHISTOQUÍMICA para SARCOMA DE EWING?

A

CD99
FLI-1
NKX2

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16
Q

INMUNOHISTOQUÍMICA NEGATIVA para SARCOMA DE EWING

A

MIOGENINA
CROMOGRANINA
CD45
MyoD1

17
Q

BIOLOGÍA MOLECULAR

A

EWSR1 /FLI-1
t(11;22)(q24;q12)

Bases (21 decks)

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