Osteoarthritis Drugs

Question 1

the drug of choice for osteoarthritis is dependent on what?

Answer 1

severity of disease and presence/absence of local inflammatory changes

Question 2

what are the drugs for osteoarthritis

Answer 2

GOT CAND

Glucocorticoids
Opioids
Tramadol
Capsaicin
Acetaminophen
NSAIDs
Duloxetine

Question 3

first line for mild to moderate osteoarthritic pain without signs/symptoms of inflammation

Answer 3

acetaminophen

Question 4

when do you use NSAIDs for osteoarthritis

Answer 4

if acetaminophen is not satisfactory or there are signs/symptoms of inflammation

Question 5

topical gel or solution for local treatment of osteoarthritis

Answer 5

Diclofenac

Question 6

what is Duloxetine in terms of osteoarthritis

Answer 6

selective SNRI used for chronic musculoskeletal pain

Question 7

opioids used as last resort for intractable osteoarthritic pain

Answer 7

hydrocodone
morphine
oxycodone

Question 8

when is Capsaicin used

Answer 8

• patients with inadequate benefit from NSAIDs
• patients that can’t tolerate NSAIDs
• when contraindications to use of NSAIDs

Question 9

adverse effects of Capsaicin

Answer 9

• severe skin burns and nerve damage at site of application

- dried residue can cause coughing, sneezing, eye irritation

Question 10

glucocorticoids used when one or few joints affected by osteoarthritis

Answer 10

Betamethasone

Triamcinolone