Autonomics Flashcards
what does the autonomic nervous system regulate
- contraction and relaxation of smooth muscle
- all exocrine and certain endocrine secretions
- heartbeat
- certain steps in intermediary metabolism
what is the predominant factor for rate in the heart
the parasympathetic system
control of BP is mainly by what system
sympathetic system
where are the muscarinic receptors
M1: ganglia
M2: heart and presynaptic nerve terminals
M3: SM, sweat glands, vascular endothelium
adrenergic receptors for liver and what is its effect
alpha 1 and beta 2
increase in gluconeogenesis and glycogenolysis
adrenergic receptors for adipocytes and its effect
alpha 2 to inhibit lipolysis
beta 3 to increase lipolysis
significance of beta 1 receptors – location and effect
heart – increase HR and contractility
juxtoglomerular cells - increase renin release
what adrenergic receptors work on pancreatic islets and its effects
beta 2 – on alpha cells it increases glucagon secretion and on beta cells it increase insulin secretion
alpha 2 - on beta cells it inhibits insulin secretion
what adrenergic receptors work on skeletal muscles
beta 2 – it increase glycogenolysis
what is the location and effect of alpha 1 adrenergic receptor
relaxation of GI /intestinal SM
contraction of vascular and genitourinary system
liver - increase glycogenolysis and gluconeogenesis
