Oncology - Hepatoblastoma Flashcards
1
Q
Defintion
A
Most common primary liver tumour in children
2
Q
Epidemiology
A
Usually diagnosed during the first 3 years of life
3
Q
Aetiology
A
Genetic mutation
Some genetic health conditions increase a child’s risk:
- Beckwith-Weidemann syndrome
- Familial adeomatous polyposis
- Glycogen storage diseases
- Aicardi syndrome
4
Q
Symptoms
A
Mass in abdomen
Abdominal pain
Loss of appetitie
Weight loss
Nausea and vomiting
Jaundice
Fever
Decreased urine output
Abdominal vein distension
5
Q
Diagnosis
A
FIRST LINE = LFTs + AFP level
CT + MRI
GOLD STANDARD = Biopsy
6
Q
Treatment
A
Surgery
Chemotherapy
Radioembolisation
Tumour ablation
7
Q
Risk factors
A
Low birth weight
