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Year 1 Summative 2 > OCB02 > Flashcards

OCB02 Flashcards

1
Q

GSC

A

Gingival

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2
Q

DPSC

A

Dental pulp

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3
Q

DFPC

A

Dental follicle

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4
Q

SHED

A

Stem cells from human exfoliated teeth

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5
Q

TGPC

A

Tooth germ progenitor cells

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6
Q

iPSC

A

Induced pluripotent

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7
Q

PDLS

A

Periodontal ligament

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8
Q

ESC

A

Embryonic

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9
Q

EOSC

A

Oral mucosa epithelial

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10
Q

GMSC

A

Gingival mucosa

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11
Q

Where do dental pulp cells come from?

A

Neural crest cells

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12
Q

What do mesenchymal cells do?

A

Grow and repair organs

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13
Q

When does primary dentine stop being formed?

A

When the bottom of the root shuts

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14
Q

What is gastrulation and where does it occur?

A

Forming the 3 germ layers in the inner cell mass

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15
Q

What does the mesoderm form?

A

Everything else

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16
Q

What does the endoderm form?

A

GI tract including the liver and pancreas

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17
Q

What does the ectoderm form?

A

Nervous system, NCC and the skin

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18
Q

Describe the lay out around the neural tube (4)

A

Ectoderm, NCC, tube, notochord and endoderm

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19
Q

What do NCC do?

A

Direct the growth and development of the face

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20
Q

What is oligodontia?

A

No teeth, cleft palate and cancer due to genetic problems

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21
Q

What does Runx2 cause?

A

Teeth continuously made

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22
Q

What is ectodermal dysplasia?

A

No glands and weird teeth due to EDAR

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23
Q

What forms the neural plate?

A

Ectoderm

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24
Q

What does the neural plate form?

A

Neural tube

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25
Q

What grows where the tube fuses?

A

Hindbrain

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26
Q

Where is the primitive streak found and what is it derived from?

A

Neural plate

Mesoderm

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27
Q

What forms somites?

A

Mesoderm

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28
Q

Where do cells from the streak move to?

A

The notochord

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29
Q

How is head to tail decided?

A

When cells leave the streak

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30
Q

How is belly to back decided?

A

Where the cells are placed on the streak

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31
Q

Describe what the primitive streak forms top to bottom

A

Vertebrae, muscles, heart, kidney, belly

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32
Q

What cells forms the neural plate?

A

Epiblast calls

33
Q

What forms the blastocyst? (3)

A

Trophoblast, epiblast then hypoblast

34
Q

What does the trophoblast form?

A

Placenta

35
Q

What does the inner cell mass formed from?

A

Hypoblast and epiblast

36
Q

What does the epiblast form?

A

Ectoderm

37
Q

What does the hypoblast form?

A

Endoderm

38
Q

What causes proliferation and the epithelium?

A

BMP4, FgF and Shh

39
Q

What does bmp stimulate?

A

Cell death

40
Q

What is under the enamel knot?

A

Dental papilla

41
Q

What does the homeobox do?

A

Genes that control other genes expression

42
Q

What gene decides how many cusps will form?

A

Barx1

43
Q

When does the enamel knot form and why?

A

At the bud stage as the mesenchyme signals it to do so

44
Q

What genes contribute to cusp formation?

A

Eda and Shh

45
Q

What forms the oral epithelium?

A

Ectoderm

46
Q

Where is the oral epithelium?

A

At the top of the circle

47
Q

Where is the dental mesenchyme?

A

In the bottom middle of the circle

48
Q

In the bell stage what type of tissue makes up the top and bottom?

A

The top is the epithelial and the bottom is the mesenchyme and NCC

49
Q

What does mesenchyme form?

A

Dentine, pulp, cementum, alveolar bone and PDL

50
Q

What does the epithelial form?

A

Enamel

51
Q

What comes from the dental follicle?

A

Cementum, PDL and alveolar bone

52
Q

What does the dental papilla form?

A

Dentine and pulp

53
Q

Name the 4 different type of cementum

A

Extrinsic acellular at the crown
Mixed cellular at the bottom of the root
Intrinsic cellular in the middle of the root
Extrinsic acellular at the edge of the root

54
Q

What does aceullar mean?

A

It doesn’t contain cells

55
Q

What is cortical and trabecular bone?

A

The outside of the bone and in the inside of the bone

56
Q

What is the difference between maxilla and mandible bone?

A

Mandible bone is regular where as maxilla is irregular

57
Q

Where are osteoclasts found?

A

In howships lacunae

58
Q

What do bone lining cells do?

A

Move P and Ca into and out of bone

59
Q

What sits next to the HERS? (2)

A

Odontoblasts and the dental follicle

60
Q

When the HERs finishes what comes above it?

A

Rests of malassez which are next to cementum

61
Q

What connects cementum and bone?

A

Collagen

62
Q

What happens to pulp in the elderly?

A

It gets more fibrous and smaller

63
Q

What may cause pulp inflammation?

A

Caries, toxins, bacteria and trauma

64
Q

What is taurodontism?

A

When the pulp splits too low

65
Q

What does the pulp do? (4)

A

Make/repair dentine, form roots, protect against infection and cause eruption

66
Q

What happens when pulp becomes inflamed?

A

Capillaries invade

67
Q

What does dentinogensis imperfecta cause?

A

Narrow roots and bulbous canals

68
Q

What causes pulp stones?

A

Tertiary dentine

69
Q

What are sclerosed canals?

A

Dentine filled canals

70
Q

What are lateral canals?

A

Ones off the sides

71
Q

What are accessory canals?

A

Ones at the bottom

72
Q

What’s the difference between coronal and reticular pulp?

A

Pseudostratified columnar while there is reticular has simple columnar and coronal is at the top while radicular is in the canals

73
Q

Where is the disc found in the TMJ?

A

On top of the condyle

74
Q

Where is the coronoid and condyle?

A

Coronoid is at the front and the other at the back

75
Q

Which bones of the TMJ are muscle attachments?

A

Coronoid and the angle

76
Q

What type of joint is the TMJ?

A

Hinge and gliding joint

77
Q

What is the ligament called that moves with the bone?

A

Mandibular fossa attached to the condyle

78
Q

What cartilage is in the TMJ?

A

Secondary

Year 1 Summative 2 (24 decks)

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