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Year 1 Summative 2 > BMS02 > Flashcards

BMS02 Flashcards

1
Q

What is the nernst equation?

A

58 x log x (conc out / conc in)

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2
Q

What is the Goldman Hodgkin Katz equation and how is it different to the Nernst equation?

A

58 x log x ((50 x K out + Na out) / (50 x K in) + Na in)

It considers the permeabilities of the ions

There is 50 times more K than Na

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3
Q

Draw glutamine

A

CH2 CH2

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4
Q

What type of collagen makes cartilage, blood vessels, tendon, bone, skin and lungs?

A

Type 2 and all others are type 1

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5
Q

What does pKa =

A

When half of the acid has dissociated

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6
Q

What is the Henderson Hasselblach equation?

A

pH = pKa + log (A / HA)

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7
Q

What 3 organs buffer in the blood?

A

Blood, kidney and lungs

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8
Q

What are the concentrations of Na, K and Cl in and out of cells?

A

Na in 10 out 140
K in 140 out 4
Cl in 4 out 140

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9
Q

What 3 things does the SER do?

A

Detoxification
Recycling
Lipid metabolism

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10
Q

What bond binds FA to glycerol?

A

Ester bonds

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11
Q

What 3 things create fluidity in the cell membrane?

A

Unsaturated fats, low cholesterol content and short FA

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12
Q

What 4 compounds may make up a phospholipid?

A

Choline
Serine
Inositol
Ethanolamine

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13
Q

What is the Michaelis Menton equation?

A

Vo = Vmax x S / Km + S

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14
Q

What is km?

A

The michaelis menton constant

E + S = ES = E + P

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15
Q

Why is 0.5 vmax special?

A

Vo = 0.5 vmax when km = S

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16
Q

When does ROR become independent from substrate concentration?

A

When S is very high

17
Q

What value will a competitive inhibitor alter?

A

Km not Vmax

18
Q

What value will a non competitive inhibitor later?

A

Vmax not Km

19
Q

What is Kcat?

A

The amount of product made fro

one enzyme

20
Q

What is an allosteric enzyme?

A

It has an allosteric site for molecules to bind to to alter catalytic abilities

21
Q

What is Kd?

A

Dissociation constant

K-1 / K1

22
Q

How do you calculate the specificity constant?

A

Kcat / Km

23
Q

Describe the lineweaver burke plot?

What occurs at the crossing of the Y and X axis

A

Y axis
1/Vo
1/Vmax

X axis
1/S
-1/Km

Year 1 Summative 2 (24 decks)

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