BMS11 Flashcards

1
Q

What is the blood vessel system called?

A

Vasa recta

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2
Q

What comes off of primary processes from the cell body?

A

Pedicles

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3
Q

What is the renal corpuscle?

A

Glomerulus, afferent and efferent arteries

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4
Q

What things can move passively into tubules?

A

Chloride, urea, potassium, hydrogen, calcium and hydrogen carbonate

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5
Q

If the afferent arteriole constricts what happens?

A

Hydrostatic pressure is lowered decreasing the glomerular filtration rate

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6
Q

What 2 things does endothelium line?

A

Lymph and blood vessels

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7
Q

Describe the tubes order (9)

A

PCT, SCT, thin loop, thing loop, thick loop, DCT, cortical CD, medullary CD and renal pelvis

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8
Q

Where is the macula densa found?

A

Lines where the DT meets the thick limb

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9
Q

Describe the bowmans wall (5)

A

Bowmans capsule, bowmans space, podocytes on the capillaries, the BM, fenestrated endothelium and then the capillary itself

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10
Q

What is the macula densa?

A

Cells that detect Na concentrations

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11
Q

Name the 2 types of nephrons

A

Cortical- short loops in the outer region

Medullary- long loops in the inner region

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12
Q

Where are mesangial cells?

A

Between capillaries in the glomerulus

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13
Q

What nervous system controls mesangial cells?

A

Sympathetic nervous system

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14
Q

What does erythropoietin do and what releases it?

A

It is released from the kidney in order to stimulate RBC production

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15
Q

Name a K sparing diuretic

A

Amiloride

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16
Q

Name a loop diuretic

A

Torsemide

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17
Q

Name a diuretic

A

Thiazide

18
Q

Where are intercalated cells and why are they called this?

A

In the collecting duct and because they have lots of mitochondria

19
Q

What does spironolactone do?

A

Compete for aldosterone receptors

20
Q

What does aldosterone do?

A

Upregulate Na pumps and make more so that more Na is excreted

21
Q

What direction does K and Na generally go?

A

K is removed and Na is added in

22
Q

What do diuretics do?

A

Increase how much salt goes into the tubules so more water is lost

23
Q

By retaining more water, what happens?

A

Blood pressure increases

24
Q

What part of the renal system fine tunes K?

A

Collectign duct

25
Q

Which ions can pass in between cells?

A

Na, K, Ca and Mg

26
Q

Which pump do thiazides act on?

A

Na/Cl in the distal tubule

27
Q

What pump is in the DCT?

A

Na and Cl in

28
Q

What pump do all elements have?

A

3Na out and 2K in

29
Q

What pump does the loop of henle have?

A

Na, K and Cl in

30
Q

Which organelle is alkali?

A

Mitochondria

31
Q

What’s the bodies optimum pH?

A

7.35-7.45

32
Q

What do increased K+ levels cause?

A

Low blood pH

33
Q

What may lower K+ levels?

A

Acidosis

34
Q

What will increase K+ secretion?

A

Increased tubular flow

35
Q

What stimulates K+ channels?

A

Aldosterone

36
Q

Why is urine acidic?

A

We excrete H and reabsorb HCO3

37
Q

What 4 things in the body act as buffers?

A

Protein
HCO3
Hb
Plasma

38
Q

How do you work out bodily pH?

A

pKa + log (HCO3 in kidneys)/(CO2 in lungs)

39
Q

What levels will the brain stem respiratory system respond to?

A

CO2
O2
H+

40
Q

What are the features of alkalosis?

A

Lots of HCO3 so lots of CO2 is made

41
Q

What are the features of acidosis?

A

Not much CO2 as all the HCO3 is being used to neutralise it

42
Q

Name 3 pumps in the tubule

A

H in
Na out/NH4 in
Glut out/Na in