nutrition: chapter 20 Flashcards
1
Q
glucose
A
primary source of energy for the body
2
Q
insulin
A
- produced by beta cells of the pancreas
- needed for glucose transport into cells
3
Q
diabetes
A
- metabolic diseases characterized by hyperglycemia
people with diabetes either:
- produce very little to no insulin (insulin deficiency)
- ineffectively use insulin (insulin resistance)
- produce inadequate insulin amount (insulin insufficiency)
4
Q
hyperglycemia
A
elevated blood sugar level
5
Q
classifications
A
- type 1 diabetes
- type 2 diabetes
- gestational diabetes
- other types
- impaired glucose tolerance
6
Q
symptoms
A
- polydipsia
- polyuria
- polyphagia
- unintentional weight loss (type 1)
- blurred vision, fatigue, dehydration, skin irritation or infection, general weakness, loss of strength
7
Q
lab tests will show
A
- hyperglycemia
- abnormal glucose tolerance tests (done in pregnancy)
- elevated glycosylated hemoglobin A1c (3 month avg.)
- glucosuria
- proteinuria
- microalbuminuria
8
Q
diabetic ketoacidosis (DKA)
A
9
Q
stages of glucose metabolism
A
- initial interchange with glycogen (glycogenolysis) and reduction to a smaller central compound (glycolysis pathway)
- joining with the other two energy-yielding nutrients, fat and protein (pyruvate link)
- final common energy production (citric acid cycle and electron transport chain)
10
Q
exogenous
A
originating from outside the body
11
Q
sources of blood glucose
A
- dietary intake
- glycogen from liver and muscles
12
Q
uses of blood glucose
A
- for immediate energy needs: glycolysis
- change to glycogen for storage: glycogenesis
- convert to fat for longer-term storage: lipogenesis
13
Q
glucagon
A
- opposes insulin
- responds to hypoglycemia
- alpha cells
14
Q
somatostatin
A
- acts as a referee for insulin and glucagon
- delta cells
15
Q
abnormal metabolism in diabetes (glucose)
A
- cells are starved for glucose
- glucose concentrations increase in the blood
- hyperglycemia results
16
Q
abnormal metabolism in diabetes (fat)
A
- lipolysis in the adipose tissue increases
- fatty acids are released in the blood
- elevated triglyceride levels result
- ketogenesis ensues in the liver
- ketones accumulate in the body
- diabetic ketoacidosis results