nutrition: chapter 20 Flashcards

1
Q

glucose

A

primary source of energy for the body

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2
Q

insulin

A
  • produced by beta cells of the pancreas
  • needed for glucose transport into cells
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3
Q

diabetes

A
  • metabolic diseases characterized by hyperglycemia

people with diabetes either:
- produce very little to no insulin (insulin deficiency)
- ineffectively use insulin (insulin resistance)
- produce inadequate insulin amount (insulin insufficiency)

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4
Q

hyperglycemia

A

elevated blood sugar level

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5
Q

classifications

A
  • type 1 diabetes
  • type 2 diabetes
  • gestational diabetes
  • other types
  • impaired glucose tolerance
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6
Q

symptoms

A
  • polydipsia
  • polyuria
  • polyphagia
  • unintentional weight loss (type 1)
  • blurred vision, fatigue, dehydration, skin irritation or infection, general weakness, loss of strength
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7
Q

lab tests will show

A
  • hyperglycemia
  • abnormal glucose tolerance tests (done in pregnancy)
  • elevated glycosylated hemoglobin A1c (3 month avg.)
  • glucosuria
  • proteinuria
  • microalbuminuria
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8
Q

diabetic ketoacidosis (DKA)

A
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9
Q

stages of glucose metabolism

A
  1. initial interchange with glycogen (glycogenolysis) and reduction to a smaller central compound (glycolysis pathway)
  2. joining with the other two energy-yielding nutrients, fat and protein (pyruvate link)
  3. final common energy production (citric acid cycle and electron transport chain)
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10
Q

exogenous

A

originating from outside the body

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11
Q

sources of blood glucose

A
  • dietary intake
  • glycogen from liver and muscles
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12
Q

uses of blood glucose

A
  • for immediate energy needs: glycolysis
  • change to glycogen for storage: glycogenesis
  • convert to fat for longer-term storage: lipogenesis
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13
Q

glucagon

A
  • opposes insulin
  • responds to hypoglycemia
  • alpha cells
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14
Q

somatostatin

A
  • acts as a referee for insulin and glucagon
  • delta cells
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15
Q

abnormal metabolism in diabetes (glucose)

A
  • cells are starved for glucose
  • glucose concentrations increase in the blood
  • hyperglycemia results
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16
Q

abnormal metabolism in diabetes (fat)

A
  • lipolysis in the adipose tissue increases
  • fatty acids are released in the blood
  • elevated triglyceride levels result
  • ketogenesis ensues in the liver
  • ketones accumulate in the body
  • diabetic ketoacidosis results
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17
Q

abnormal metabolism in diabetes (protein)

A
  • protein tissues are broken down
  • weight loss, muscle weakness, and urinary nitrogen loss result
18
Q

long term complications

A
  • retinopathy (eye damage)
  • nephropathy (kidney damage)
  • neuropathy (nerve damage)
  • heart disease
    • dyslipidemia
    • hypertension
19
Q

postprandial

A

after eating; normally 1-2 hours after a meal

20
Q

Cushing’s syndrome

21
Q

glucagonoma

A
  • rare neuroendocrine tumor
  • found in alpha cells of pancreas
  • leads to overproduction of glucagon
  • may cause diabetes, weight loss, high glucagon levels, and hypoaminoacidemia
22
Q

pheochromocytoma

A
  • tumor of the adrenal medulla or the sympathetic nervous system
  • affected cells secrete excess epinephrine or norepinephrine
  • causes headache, hypertension, and nausea
23
Q

hypoglycemia

A

low blood glucose level

24
Q

GLUT4

A

insulin-regulated protein that is responsible for glucose transport into cells

25
ketogenesis
production of ketones in the body (occurs in the liver)
26
ketones
acids that occur as intermediate products of fat metabolism
27
acetone
- major ketone compound - results from fat breakdown for energy in individuals with unmanaged diabetes
28
albuminuria
high levels of albumin in the urine
29
estimated glomerular filtration rate (eGFR)
equation used to measure kidney function
30
cellulitis
- diffuse inflammation of soft or connective tissues from injury, bruises, or pressure sores that leads to infection - poor care may result in ulceration and abscess or gangrene
31
glycemic control
management of blood glucose levels within individualized targets
32
insulin secretagogues
- oral medication - stimulates beta cells to secrete insulin - lowers overall blood glucose levels - increases risk of hypoglycemia and weight gain
33
early detection and monitoring
- community screening programs - annual physical examinations - fasting blood glucose, HbA1c
34
basic goals of care
- exogenous insulin - oral/ non-insulin injectable meds - maintaining healthy eating patterns - 150 minutes of moderate-intensity aerobic physical activity weekly
35
Diabetes Self-Management Education and Support (DSME/S)
- dietary and lifestyle management - monitoring - medications - problem solving - reducing risk - psychosocial assessment and care - resource awareness
36
MNT
prediabetes: - healthy dietary pattern, physical activity, weight loss diabetes: - individualized nutrition therapy
37
nutrient balance
- starch and sugar - glycemic index - sugar substitutes and sweeteners - protein - fat
38
nutrient intake, physical activity, and medication timing
- daily schedule - physical activity and glycemic management - meds and meal timing - carbohydrate counting - healthy eating patterns (t2/prediabetes)
39
additional concerns
- "diabetic" foods - alcohol - hypoglycemia - illness - travel - eating out - stress
40
diabetes distress
psychological reaction to the intense emotional burden and negative impact of daily concerns when managing the serious and complex lifelong disease of diabetes