Normal Anatomy (Pancreas & Liver) Flashcards
What region is the pancreas located in?
-the epigastric region, close to the midline
What happens to the pancreas with age?
- decreases in size
- increases echogenicity
What tissue is the pancreas composed of?
-exocrine and endocrine (mostly exocrine)
What are the functions of the pancreas?
Exocrine
- digestion
- secretes pancreatic juice
- breaks down fat, carbohydrates and proteins
Endocrine
- hormones (glucagon and insulin)
- maintain sugar and salt balance
Acini Cells
- exocrine
- 80% performs exocrine functions
- small grape like structures with endocrine tissue in between
What is pancreatic juice composed of?
- amylase (carbohydrates)
- lipase (fats)
- trypsin (protein)
- chymotrypsin (protein)
- carboxypepidase (protein)
- nucleases (nucleic acids)
- sodium bicarbonate (neutralize hypochlorite acid)
What do digestive hormones do?
- release is stimulated by partially digested food
- cause the production of pancreatic juices
What are the Pancreatic Digestive Hormones?
- cholecystokinin, gastrin and acetylcholine (stimulate acini cells to produce digestive enzymes)
- secretin (stimulates production of sodium bicarbonate)
What is the main pancreatic duct?
Duct of Wirsung
What is the accessory duct?
Duct of Santorini
How does digestion occur?
- pancreatic juice collects in the Duct of Wirsung, then moves into the duodenum through the Ampulla of Vater
- the Sphincter of Oddi relaxes to allow the passage of juices
Endocrine Function
-secretes hormones directly into blood stream
What does the Islets of Langerhans consist of?
- alpha cells
- beta cells
- delta cells
What are the 3 pancreatic hormones?
- insulin
- glucagon
- somatostanin
Insulin
-glucose to glycogen
Glucagon
-glycogen to glucose
Somatostanin
-alpha and beta inhibitor (inhibit insulin and glucagon production)
What does the pancreaticoduodenal artery supply?
-supplies pancreas head and part of the duodenum
What do the branches of the splenic artery supply and where are they located?
- body and tail of pancreas
- courses on the superior edge (before it enters spleen)
- tortuous
Venous (pancreas)
-tributaries of SMV and SV
Is the pancreas retroperitoneal of intraperitoneal?
retroperitoneal
What are the 3 key regions of the pancreas?
- head
- body
- tail
What is the 4th region of the pancreas?
-the neck
Where is the pancreas head located?
-more inferior to the body and tail
Where is the pancreas neck and body located?
-more superficial than head and tail
Where is the pancreas tail located?
- more superior
- towards the spleen
What is the echogenicity of the pancreas?
- usually isoechoic or hyperechoic to the liver
- increases in echogenicity with age
- uncinate process can appear hypoechoic to the rest of the pancreas
What is the echotexture of the pancreas?
-homogenous (can have a mottled appearance)
Size of Pancreas
- size is comparable between males and females
- head is usually largest in dimension
- neck is usually the smallest
- body and tail are slightly smaller than head
Pancreas Shape
-varies
Pancreas Contour
- usually smooth (occasionally lobulated)
- if increased in echogenicity with age it can blend into retroperitoneal fat, making it hard to tell true size and contour
Landmarks for the Pancreas Head
- gastroduodenal artery (GDA): anterior lateral aspect of pancreas head and the second part of the duodenum lies lateral to the GDA
- common bile duct (CBD): posterior lateral aspect of head
- inferior vena cava (IVC): posterior
Pancreas Neck Landmarks
-anterior to the SMV and portosplenic confluence
Pancreas Body Landmarks
- superior mesenteric artery (SMA): easiest to find
- splenic vein (SV)
- superior mesenteric vein (SMV)
- body is medial to the portosplenic confluence