Anatomy & Physiology Flashcards
What are muscles responsible for?
- movement
- heat production
- posture
What are the characteristics of skeletal muscle tissue?
- excitability: stimulated
- contractility: contract/shorten
- extensibility: stretch/extend (muscles return to ‘resting’ length)
3 Types of Muscle Tissue
1) skeletal
2) cardiac
3) smooth
What is another name for skeletal muscle?
- striated
- voluntary
How much of body weight is skeletal muscle?
40%-50%
Skeletal Muscle
- attached to bone
- microscopic striations
- voluntary contractions
- multiple nucleus’ (on periphery of cell)
4 Parts of a Skeletal Muscle Cell
1) cells = fibres (threadlike)
2) plasma membrane = sarcolemma
3) cytoplasm = sarcoplasm
4) endoplasmic reticulum = sarcoplasmic reticulum (SR), calcium release and storage
What do muscle fibres contain?
- many mitochondria, nuclei and myofibrils
- T Tubules
T Tubules
- inward extensions of the sarcolemma
- allow nerve impulses to move deeper into the fibre
Myofibrils
-numerous fine fibres packed close together in the sarcomere
What are myofibrils made of?
-myofilaments (fine, threadlike structures)
How many types of protein make up myofilaments?
4
Myosin
-makes up thick myofilaments
Actin
-makes up thin myofilaments
Sarcomere
-repeating segments of actin and myosin
What is the basic functional unit of muscle fibres?
sarcomere
How are individual sarcomeres separated?
-z lines (disks)
Neuromuscular Junction
-microscopic ‘gap’ called the synapse, between the end of the motor neurone and the sacrlemma
When will a skeletal muscle stay at rest until?
-it is stimulated by a nerve impulse, which arrives via a motor neurons
The nerve impulse travels along the motor neurone until it reaches the…
neuromuscular junction
How are neurotransmitters released?
nerve impulses are transmitted across the synapse
Where do neurotransmitters and receptors bind?
sarcolemma
What happens when the neurotransmitters bind with the receptors at the sarcolemma?
trigger the SR to release Ca++ into the sarcoplasm
What plays a role in the binding of myosin and actin?
the Ca++ released by the SR
What happens between myosin and actin during contraction?
- form ‘cross bridges’
- act as levers to pull myofilaments past each other
What happens as a muscle contracts?
-myofilaments slide past eachother
What does contraction require?
- calcium (cross bridge)
- ATP (for energy)
How do you stop contraction?
-SR actively removes Ca++
Aerobic
- occurs when oxygen levels are normal
- supplies energy for long periods of time
- example: walking
Anaerobic
- occurs when oxygen levels are low
- fast process
- supplies energy for a few mins of maximal exercise
- example: 100m sprint
What does anaerobic activity result in?
-production of lactic acid and lack of oxygen (since oxygen is required to convert lactic acid back into glucose)
What produces lactic acid?
- contraction when there is not enough oxygen
- results in muscle soreness
Why do we breathe heavily after exercise?
-to make up for oxygen debt
What does fatigue lead to?
- reduced strength
- loss of muscle’s ability to contract
- depletes cellular ATP store
Where does energy for contraction come from?
-breaking ATP bonds
Motor Neuron
-specialized nerve fibre that transmits an impulse to a muscle, causing contraction
Neuromuscular Junction
-specialized point of contact between a nerve ending and a muscle fibre
Motor Unit
a motor neuron + the muscle cell it innervates
How does the number of fibres in a motor unit affect it?
- fewer fibres: more precise
- more fibres: more powerful
Neurotransmitters
- released by the motor neurone in response to a nerve impulse
- start actions inside the muscle fibre that initiate contraction
5 Types of Muscle Contractions
- twitch
- tetanic
- tonic
- isotonic
- isometric
Myography
-method of graphing the changing tension of muscle as it contracts
Twitch Contractions
- quick, jerky response to stimulus
- ‘lab phenomena’ (not related to normal muscle activity)
- in isolated muscle fibres
Tetanic Contraction
- sustained and steady
- caused by a series of stimuli bombarding a muscle in rapid succession
- this series of stimuli ‘join forces’ to produce a sustained/prolonged contraction (tetanus)
- calcium dependant
- example: lock jaw
Tonic Contraction
- continual and partial
- at any time, a few muscle fibres are contracting
How is muscle tone maintained?
negative feedback
Flaccid
muscles have less tone than normal
Spastic
muscles have more tone than normal
What does the strength and time of skeletal muscle contraction depend on?
- metabolic condition
- number of fibres contracting
- number of motor units involved
- intensity
- frequency
What is a muscles maximum strength dependant on?
-initial length of its fibres (the longer, the more they contract/shorten)
What happens to a skeletal muscle if the sarcomeres are compressed?
-reduces the muscles ability to compress
What happens if sarcomeres are overstretched?
-actin and myosin are too far apart to bind
When does the strongest muscle contraction occur?
-when the muscle is stretched to its optimal length
Isotonic Contractions
- produces movement at a joint
- muscle changes length
- tension stays the same
Concenteric Contraction
- muscle shortens as it contracts
- insertion end of muscle moves toward the origin
Eccenetric Contraction
- muscle lengthens while contracting
- produces tension
- insertion moves away from point of origin
Most types of body movements are…
isotonic contractions
Isometric Contractions
- tension within muscle increases, but muscle doesn’t shorten (no movement)
- example: pushing against a wall
- muscle length is the same contracted or relaxed
What are repeated isometric contractions cause?
stronger muscles
Effects of Exercise on Skeletal Muscles
- improves muscle tone
- improves posture
- better heart and lung function
- reduces fatigue
- develops muscle tissue
- maintain healthy weight
What causes atrophy?
-long periods of time without activity
What causes hypertrophy?
-regular exercise
What do exercises such as weight lifting, squats and planking (strength training) do to skeletal muscles?
- increases number of myofilaments in each muscle fibre
- increases total mass of muscle
- does NOT increase number of muscle fibres
What do endurance exercises (aerobic training) do for skeletal muscles?
- allows more efficient delivery of oxygen and nutrients to a muscle (increased blood flow)
- increase the number of mitochondria in muscle
- does NOT result in muscle hypertrophy
Cardiac Muscle
- composes bulk of heart
- loaded with mitochondria
- doesn’t run low on mitochondria
- no fatigue
Intercalated Disks
- dark bands that join branches of cells
- enables heart to contract
Are cardiac muscles voluntary of involuntary?
involuntary
Do cardiac muscles have more than one nucleus?
Yes, many nuclei are centrally located.
Smooth Muscle
- myofibrils not organized into sarcomeres
- walls of hollow visceral structures (digestive tract, blood vessels, ureters)
- single unit and multi unit
Smooth muscles are also called…
- non striated
- involuntary
- visceral
Do smooth muscles have more than one nucleus?
No, they have one, centrally located nucleus.
What does muscle function depend on?
- bones and joints
- respiratory, circulatory, nervous, and skeletal systems
What is the nervous system made up of?
- brain
- spinal cord
- nerves: cranial and spinal
What 2 parts is the nervous system divided into?
- CNS
- PNS
CNS
- brain and spinal cord
- ‘centrally located’
- structural and functional centre of the entire nervous system
- control centre: interprets incoming (sensory) info and sends out a response
PNS
- nerves that extend to ‘peripheral’ parts of the body (from the brain and spinal cord)
- communication network between CNS and the rest of the body
Afferent Division
- INCOMING sensory pathways
- sensory info from visceral effectors to CNS
Efferent Division
- OUTGOING motor pathways
- motor info from CNS to visceral effectors
Somatic
-communication between CNS and skeletal muscles
Autonomic
-communication between CNS and ‘visceral effectors’ (smooth muscles, cardiac muscles, glands, adipose, etc)
Sympathetic
- fight or flight
- stress response activities
Parasympathetic
- rest and repair
- normal resting activities
What are the 2 subdivisions of the PNS?
- automatic NS
- somatic NS
Automatic Nervous System (ANS)
- involuntary
- visceral motor nerves
- impulses from CNS to cardiac muscles, smooth muscles and glands
Somatic Nervous System (SNS)
- voluntary
- somatic motor nerves
- impulses from CNS to skeletal muscle
What are the 2 types of cells in the NS?
- glia/neuroglia (supporting)
- neurons (nerve cells)