NMS, Agranulocytosis

Question 1

Agranulocytosis s/s (5)

Answer 1

pallor
fatigue
headache
fever
nosebleeds

Question 2

What medications can cause agranulocytosis (2)

Answer 2

Carbamazepine/Tegretol

Question 3

Agranulocytosis

Answer 3

a life-threatening condition that involves having severely low levels of white blood cells called neutrophils. White blood cells are part of your immune system. They protect your body from infection by fighting off germs that make you sick.

Question 4

Normal range of WBC count

Answer 4

4500-11000

Question 5

Neuroleptic malignant syndrome (7)

Answer 5

life threatening

starts with confusion, muscular rigidity, fever, increase HR, can progress to rhabdomyolysis (Muscle breakdown increased levels of CK, K, WBC’s)

Question 6

Rhabdomyolysis can progress to

Answer 6

kidney and heart failure

Question 7

Tx for NMS?

Answer 7

D/C antipsychotic
give dantrolene (protects ANS)
dopamine agonists

Question 8

NMS kidney disease pneumonic (6)

Answer 8

NMS

Kidney = increase in (K) potassium
increase in CK
Increase in killer cells (WBC’s)

Disease = D/C Meds
dantrolene
dopamine agonist (3 D’s)