Brain & Neurotransmitters Flashcards

1
Q

Cerebellum plays a role in (4)

A

Coordination, Balance, Gross & Fine Motor skills, Hand-eye coordination

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2
Q

Increase in levels of ______ releasing hormone in the ____,____,____ increase symptoms of anxiety

A

Corticotropin, Amygdala, hippocampus, locus coeruleus

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3
Q

Most abundant Neurotransmitter in the brain is

A

GABA

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4
Q

GABA is known to be a

A

Calming neurotransmitter

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5
Q

How does GABA affect anxiety?

A

decrease in GABA increases anxiety

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6
Q

How does GABA help with relaxation and stress

A

by decreasing neuronal excitability

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7
Q

When GABA is not regulated well it can contribute to what disorders?

A

Anxiety, epilepsy, and neurological disorders

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8
Q

ACH is synthesized

A

nucleus of meynert

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9
Q

ACH is involved with (3)

A

Memory, learning, muscle movement

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10
Q

Deficits of ACH can cause

A

cognitive decline

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11
Q

Glutamate is involved in

A

cognitive functions, learning memory

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12
Q

D/O involving ACH include

A

Alzheimers & Dementia

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13
Q

Dopamine is produced in (3)

A

Substantia nigra to regulate motor movements, nucleus accumbens (implicated in causing addiction)** , ventral tegmental area

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14
Q

Dopamine influences (4)

A

reward, pleasure, motivation, movement

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15
Q

Dopamine imbalances can cause (2)

A

Psychosis and the high found in drug use

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16
Q

Dopamine disorders include (4)

A

schizophrenia, BP, addiction, depression

17
Q

Serotonin is produced in

A

Raphe of Nuclei of brainstem

18
Q

Serotonin regulates (5)

A

mood, appetite, sleep memory, and learning

19
Q

low serotonin can cause

A

mood disorder

20
Q

Serotonin disorders include (3)

A

Depression, anxiety, OCD

21
Q

Norepinephrine is produced (2)

A

locus coeruleus & medullary reticular formation

22
Q

Norepinephrine affects (6)

A

attention, focus, mood regulation, sleep wake cycle, memory formation, fight/flight

23
Q

Norepinephrine imbalances can cause

A

anxiety and depression

24
Q

Imbalances in glutamate can cause

A

mood disorders and neurodegeneration

25
Disorders with Glutamate include
schizophrenia and BP and MDD
26
Apoptosis (4)
neuronal loss of cell death cell extinction cell shrinkage cell disintegration
27
Addiction neurotransmitters (2)
Dopamine GABA
28
Nightmares neurotransmitters (5)
NE (MOST IMPORTANT) Serotonin ACH Glutamate Dopamine
29
Alcohol neurotransmitters (2) what happens with chronic alcoholism
GABA is up-regulated (increase GABA activity) and NMDA (glutamate receptors are down-regulated - decreased activity) if someone becomes a chronic drinker it becomes the opposite effect (glutamate increases, and GABA becomes down-regulated)
30
Glutamate is the most ______ neurotransmitter
excitatory
31
GABA is the most abundant what neurotransmitter
Calming
32
Stimulants neurotransmitters (3)
Catecholamines (dopamine & NE) serotonin
33
Heroine (opioid) (3)
ACH, Dopamine, NE
34
Mood disorder neruotransmitters
Serotonin, NE, Dopamine, GABA, Glutamate Serotonin and NE are the MAJOR two***
35
Infection effects c-reactive and WBCs how?
increased in c-reactive protein levels and increased WBCs
36
Histamine receptor implicated in insomnia is
H1 receptor
37
What brain wave is associated with insomnia
alpha wave activity
38
The autoimmune disease it affects cytokines by
increasing cytokine levels
39
signs of lead poisoning older homes (1970s)
developmental delay learning difficulties irritability loss of appetite weight loss sluggish and fatigue abdominal pain vomiting constipation hearing loss seizures pica