Neurotransmitters Flashcards
Acetylcholine
A neurotransmitter active in both sympathetic and parasympathetic nervous system. Preganglionic neuron releases Ach in both systems; postganglionic neuron releases norepinephrine in sympathetic and more Ach in parasympathetic. Generally considered as excitatory signal since it’s linked to attn and arousal in CNS. Produced by choline acetyltransferase
GABA and glycine
stabilizes brain activity by causing hyperpolarization of postsynaptic membrane, lets Cl- into the cell to cause hyperpolarization
Glutamate
opposite of glycine; excites
Endorphins
natural painkillers, PEPTIDE NEUROTRANSMITTERS
Seratonin
mood, eat, dream, sleep (“meds”); satiety and inhibition in mesolimbic reward pathway
Dopamine
movement and posture; promotes desire in mesolimbic reward pathway
Nor/epinephrine
Secreted by adrenal medulla; awake and alertness, fight or flight
Examples of catecholamines and their role
seratonin, nor/epinephrine, dopamine; emotion
Cause of schizo vs Parkinson’s
too much dopamine vs too little dopamine
Antagonist vs agonist
something else opposes the true effect vs something else mimics the true effect
3 categories of neurotransmitters and their examples
amino acid neurotransmitters (ex: GABA, glycine; glutamate), monoamine neurotransmitters (ex: serotonin, nor/epinephrine, dopamine) aka catecholamines, peptide neurotransmitters (ex: endorphins)